中国近视患者的角膜厚度与屈光度关系的研究  

Study on the correlation between pachymetry and diopter of myopic eyes in china

作　　者：杨斌[1] 王铮[1] 黄国富[1] 张醇[1] 吴君舒[1] 禤俭环[1] 李春满[1] 

机构地区：[1]中山大学中山眼科中心眼科医院,广州510060

出　　处：《中国实用眼科杂志》2004年第7期516-518,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的　了解我国近视眼患者角膜厚度 ,及其与屈光度的相互关系 ,并给出由屈光度预测角膜厚度的回归方程 ,为准分子激光原位角膜磨镶术 (LASIK)手术设计提供参考依据。方法　应用OrbscanⅡ眼前节系统对 45 9例近视眼患者角膜厚度进行检测 ,包括角膜中央直径为 2mm及角膜中周部上方、颞上、颞侧、颞下、下方、鼻下、鼻侧、鼻上、上方 9个直径为 2mm的测量区 (距视轴3mm)的平均角膜厚度 ;屈光度由 -0 5D至 -2 3 5D不等 ;并对各方位角膜厚度与屈光度作直线相关 ,如有相关性则进行回归分析。结果　中国近视眼患者角膜厚度以中央区最薄 ,鼻上方最厚 ,近视眼患者角膜最薄点多位于颞下方 ( 5 2 72 % ) ;颞下及颞侧角膜厚度与屈光度呈线性负相关 (相关系数r分别为 -0 117、 -0 10 7,P <0 0 5 0 ) ;其它部位与屈光度无相关关系 ;角膜厚度彩色地形图中均为圆形最多 ,依次为椭圆形、偏心圆形、偏心椭圆形。结论　中国近视眼患者角膜厚度的改变多位于颞下及颞侧 ,且角膜厚度随近视度数增加有变薄倾向 ;而最薄点、中央区、颞上、鼻下、鼻侧、鼻上、上方、下方角膜厚度与近视度数增加无关 ;OrbscanⅡ眼前节系统能了解角膜厚度分布情况 。Objective To evaluate the corneal pachymetry and the correlation between pachymetry and diopter of myopic eyes in china.Methods The OrbscanⅡ corneal topography system was used to investigate corneal pachymetry on 459 myopia subjects.The investigated sites(diameter is 2mm and 3mm away from visual axis)include corneal centre,superior and inferior part of cornea,superotemporal,inferotemporal,superonasal,inferonasal quarter,temporal and nasal side.The diopter is from -0 50D to -23 50D.The linear correlation between pachymetry and diopter was done.Results The mean corneal thickness of myopic eyes is the least in the centre and the greatest in superonasal quarter.The thinnest point of conea are most located in the inferotemporal.The corneal pachymetry of inferotemporal quarter and temperal side are negatively correlated to diopter(r=-0 117,-0 107, P <0 050).For the color-coded map of corneal thickness,round shape is the commonest type,followed by oval type,eccentric round shape and eccentric oval shape.Conclusions The coneal thickness of inferotemporal quarter and temporal side have the tendency to decrease when the diopter of myopic eyes increase.OrbscanⅡcorneal topography system is a useful instrument for the evaluation of corneal thickness,which has wide usefulness in corneal refractive surgeries.

关 键 词：中国 近视 角膜厚度 屈光度 OrbscanⅡ眼前节系统 

分 类 号：R778.11[医药卫生—眼科]