癌细胞对血清光谱的影响  

Effect of Cancer Cells on the Spectra of Serums

作　　者：葛向红[1] 赵元黎[1] 张凤秋[1] 张录[2] 姚淑霞[1] 秦英[1] 

机构地区：[1]郑州大学物理工程学院,河南郑州450052 [2]郑州市骨科医院,河南郑州450052

出　　处：《光谱学与光谱分析》2004年第7期841-843,共3页Spectroscopy and Spectral Analysis

基　　金：国家自然科学基金 (1 0 2 0 50 1 3)资助项目

摘　　要：研究了在血清中加入不同剂量的癌细胞对血清光谱的影响。比较了两种癌细胞的光谱 ,并与正常血清的谱线做了比较。实验结果表明 :随着癌细胞个数的降低 ,吸收谱和荧光谱强度均呈增加趋势 ,但增加到一定程度时又开始下降 ;正常血清的谱线强度明显较强。结论 :荧光光谱表明癌细胞抑制了正常血清中某种基团的振动 ,吸收光谱则表明癌细胞抑制了酪氨酸对光的吸收。This article studied the different effects on the spectra of serums by adding different amount of cancer cells into serum, and gives the comparison between CNE cells' serum spectra and Hela' as well as that between abnormal serums and normal ones. Experiment results showed that the intensity of the absorption spectra and the fluorescence spectra exhibits a trend that it increases with the decrease in the cancer cells' number, while begins to drop when it goes up to a certain extent. The intensity of the normal serums' spectra is obviously higher than that of the abnormal one. It is concluded that the changes in the intensity of fluorescence spectra' show that the cancer cells restrain the vibration of some group in the normal serums, and the absorption spectra' reveal that the cancer cells prevent the casein from absorbing light.

关 键 词：癌细胞 血清 荧光光谱 吸收光谱 诊断 

分 类 号：R730.4[医药卫生—肿瘤]