米非司酮治疗子宫肌瘤的剂量探讨  

Study on Different Doses Mifepristone in Treatment of Hysteromyoma

作　　者：王正峰 王维东[2] 

机构地区：[1]江苏省盐城市计划生育指导所,224002 [2]江苏省建湖县计划生育指导站

出　　处：《中国计划生育学杂志》2004年第7期419-421,共3页Chinese Journal of Family Planning

摘　　要：目的:探讨米非司酮治疗子宫肌瘤的剂量。方法:将81例确诊为子宫肌瘤的患者随机分成3组,Ⅰ组口服米非司酮25mg/d×3个月;Ⅱ组口服米非司酮12.5mg/d×3个月;Ⅲ组口服米非司酮6.25mg/d×3个月。结果:用药过程中3组肌瘤均有不同程度的缩小,贫血得以纠正,围绝经期可致绝经。结论:12.5mg/d剂量米非司酮连服3个月为一疗程的治疗方案,副反应轻,疗效与25mg/d组无显著差异,费用可以减少50％。Objective:To study doses of mifepristone in the treatment of hysteromyoma. Methods: 81 patients who had hyste-romyoma were divided into three groups. Ones in group Ⅰ ,Ⅱ and Ⅲ took 25 mg mifepristone a day for three months, 12. 5 mg mifepristone a day for three months and 6.25 mg mifepristone a day for three months, respectively. Results; The varying degrees of hysteromyoma reduced in three groups during the treatment. Anemia was vanishing and perimenopause turned into menopause. Conclusion: A smaller dose of mifepristone (12. 5mg/d)had less side effect, coequal curative effect and less expenses comparing with larger dose (25 mg/d) in group Ⅰ.

关 键 词：米非司酮 子宫肌瘤 剂量 肿瘤 

分 类 号：R737.33[医药卫生—肿瘤]