乳晕真皮内注射蓝色染料法前哨淋巴结活检的应用  

Application of sentinel lymph node biopsy by subareolar injection of blue dye in the treatment of breast carcinoma

作　　者：肖晖[1] 李志霞[1] 陈笑[1] 龚家镇[1] 

机构地区：[1]首都医科大学附属北京同仁医院普外科,100730

出　　处：《中华外科杂志》2004年第13期806-807,共2页Chinese Journal of Surgery

摘　　要：目的　探讨使用乳晕真皮内注射蓝色染料法前哨淋巴结活检在早期乳腺癌治疗中的作用和价值。方法　回顾性分析 2 5例早期乳腺癌患者应用乳晕真皮内注射蓝色染料法前哨淋巴结活检的临床结果。结果　 2 5例患者中成功检测出前哨淋巴结者 2 4例 ,检出率为 96 0 %。共检出前哨淋巴结 6 2枚 ,平均每例 2 5枚。病理结果中HE染色 5例淋巴结有转移 ,免疫组化染色 7例阳性。本组前哨淋巴结检出的灵敏度为 87 5 % ;准确性 96 0 % ;假阴性率 12 5 % ;假阳性率 0。Objective To probe into the feasibility and accuracy of sentinel lymph node biopsy by subareolar injection of blue dye in the treatment of early stage breast carcinoma. Methods Retrospective analysis of 25 cases of early stage breast cancer who were carried out subareolar injection of blue dye method for sentinel lymph node biopsy. Results Of 25 cases, 24 were checked out sentinel lymph nodes. Check out rate was 96 0%. Totally 62 sentinel lymph nodes were checked out, each patient had 2 5 nodes averagely. There were 5 cases with lymph node metastases in HE stain, and 7 cases with positive nodes in IHC stain. Sensitivity in this group was 87 5%; Accuracy 96 0%; False negative rate 12 5%; False positive rate 0. Conclusion Application of sentinel lymph node biopsy by subareolar injection of blue dye in the treatment of early stage breast carcinoma can also acquire high check out rate and high accuracy.

关 键 词：乳腺肿瘤 前哨淋巴结活组织检查 治疗 免疫组化染色 

分 类 号：R737.9[医药卫生—肿瘤]