部分喉切除术中影响切缘结果的因素分析  

An Analysis of The Factors Affecting The Incidence of Positive Surgical Margin in Partial Laryngectomy

作　　者：夏良平[1] 曾宗渊[1] 陈直华[1] 陈明远[1] 

机构地区：[1]中山大学肿瘤防治中心,广东广州510060

出　　处：《肿瘤学杂志》2004年第4期220-222,共3页Journal of Chinese Oncology

摘　　要：[目的]探讨影响喉癌部分喉切除术阳性切缘发生的因素。[方法]分析115例术中留取切缘标本的喉癌病例切缘阳性的发生与肿瘤部位、T分期、病理学分级、手术方式和肿瘤生长方式的关系。[结果]单因素分析显示切缘阳性发生率与肿瘤部位、T分期、病理学分级和手术方式没有明确关系,而与肿瘤生长方式有明显关系浸润性生长者切缘阳性率高于外生性生长者(12.5%比30.6%,χ2=5.702,P=0.024);多因素分析也显示只有肿瘤生长方式与切缘阳性率的发生有关(P=0.030)。[结论]喉癌部分喉切除术切缘阳性发生率与肿瘤部位、T分期、病理学分级和手术方式没有明确关系,而与肿瘤生长方式有关。To investigate the factors affecting the incidence of positive surgical margin in partial laryngecto-my.One hundred and fifteen cases with laryngeal carcinoma underwent partial laryngectomy.The relation-ship between positive surgical margin and T stage,tumor site,grade,surgical modality and tumor growth modality were studied.The univariate analysis revealed that the incidence of the positive surgical margin had no significant relationship to T stage,tumor site,grade,surgical modality,but had significant relationship to the growth modality:the incidence of positive surgical margin of endogenic tumor was higher than that of exogenic tumor(12.5%vs30.6%,χ 2 =5.702,P=0.024).The relationship between the tumor growth modality and incidence of posi-tive surgical margin was conformed by the multivariate analysis(P=0.030).[Conclusion]The incidence of positive surgical margin has significant relationship to tumor growth modality but no significant relationship to tumor site,T stage,grade and surgical modality.

关 键 词：喉肿瘤 影响因素 切缘 

分 类 号：R739.65[医药卫生—肿瘤]