肝局灶性结节性增生11例病理组织学观察  

Focal Nodular Hyperplasia in The Liver:A Pathological Analysis of 11 Cases

作　　者：潘毅[1] 牟凌骏[1] 郑舟军[1] 应李雄[1] 王丽君[1] 任国平[1] 

机构地区：[1]浙江大学医学院附属第一医院,浙江杭州310003

出　　处：《肿瘤学杂志》2004年第4期246-248,共3页Journal of Chinese Oncology

摘　　要：[目的]探讨肝局灶性结节性增生(FNH)的病理形态学特点。[方法]回顾性分析11例肝局灶性结节性增生,采用HE染色并结合组织化学网状纤维染色及免疫组织化学EnvisionTM法观察其形态特点。[结果]肉眼病灶中央常有纤维瘢痕,组织学8例为经典型,2例为毛细血管扩张型,1例为混合型。[结论]FNH为肝脏良性增生性病变,组织学上应与肝腺瘤样增生结节、肝细胞腺瘤、AFP阴性的肝细胞肝癌和纤维板层层状肝细胞癌进行鉴别。To explore the pathological characteristics of focal nodular hyperplasia(FNH)in the liver.Eleven cases with FNH were studied retrospectively by using routinely processed HE and immunohistochemical staining.Eight female and3male FNH patients aged19to54(mean32).Most of the lesions contained central scars microscopically.Eight cases were classical type;2cases,telangiectic type;and1case,mixed type microscopically.[Conclusion]FNH is a benign hyperplastic lesion of the liver.It should be differentiated from hepatic adenomatous hy-perplasia nodule,hepatocellular adenoma,alpha-fetoprotein negative hepatocellular carcinoma and fibrolamellar hepato-cellular carcinoma histologically.

关 键 词：肝局灶性结节性增生 病理学 病理诊断 

分 类 号：R730.26[医药卫生—肿瘤] R735.7[医药卫生—临床医学]