脑膜瘤术后复发的相关因素分析  

Correlated factors on postoperative recurrence of meningiomas

作　　者：滕良珠[1] 张炳杰[1] 赵旭[1] 孙为群[1] 郭华[1] 许加军[1] 

机构地区：[1]山东省立医院神经外科,山东济南250021

出　　处：《山东大学学报（医学版）》2004年第3期305-308,共4页Journal of Shandong University:Health Sciences

摘　　要：目的:探讨脑膜瘤切除术后复发的相关因素?方法:对24例复发性和122例非复发性脑膜瘤的临床资料?CT和病理学改变进行了对比分析,其中66例行FCM检测?结果:肿瘤的切除程度,病理检查见核多形性?局灶性坏死?脑浸润?血管成分增多,FCM检查见超二倍体?高DNA指数(DI)?高增殖指数(PI)等与复发显著相关?CT示肿瘤呈结节状或蕈形?有明显瘤周水肿者肿瘤易于复发?结论:肿瘤切除不彻底,CT示肿瘤为结节状或蕈形,有明显瘤周脑水肿,病理及FCM表现为肿瘤增殖活跃者,肿瘤易于复发?Objective: To study the correlated factors of the tumor recurrence after the meningioma removal. Methods: The clinical, CT and pathological data of 24 recurrence and 122 primary meningiomas were studied. Among them, FCM data of the tumor tissues of 66 cases were analysed. Results: The correlated factors of tumor recurrence may be as follows: the grade of tumors' resection, the appearance of the nuclear pleomorphism, the focal necrosis, the brain infiltration, the increased vascularity found in the pathological examination, and hypodiploidy, the high DI and PI on the FCM analysis. These factors were all correlated with the tumor recurrence significantly. If the tumors margin was nodular or mushroom-shaped and severe peritumoral edema on CT, the tumor had a tendency of recurrence. Conclusions: If the tumor was partially resected, or the tumor was nodular or mushroom-shaped and accompanied by severe peritumoral edema on CT, or appeared active growth on the pathological and FCM examination, the tumor usually had the tendency of recurrence. [

关 键 词：脑膜肿瘤 复发 因素分析 统计学 流式细胞术 

分 类 号：R739.41[医药卫生—肿瘤]