武警部队35岁以上人群血浆纤维蛋白原水平及其与脑血管病关系的调查  

Investigation of serum fibrinogen levels in Armed Police Forces personnel aged 35 years and over,and relationships between fibrinogen levels and stroke and associated risk factors

作　　者：刘绪宏[1] 马维亚[2] 张辉[1] 钱华珍[1] 束慧清[1] 

机构地区：[1]武警江苏总队医院内一科,扬州225003 [2]武警总医院神经内科,北京100039

出　　处：《武警医学》2004年第6期427-429,共3页Medical Journal of the Chinese People's Armed Police Force

基　　金：武警部队立项课题 (WKH2 0 0 10 82 )

摘　　要：目的　了解武警部队 35岁以上人群血浆纤维蛋白原 (Fg)水平 ,进一步阐述其与脑卒中及相关危险因素之间的关系。方法　在武警部队 12个省 2 4站点共 2 3130 8人中 ,以整体抽样的方法 ,随机抽取 35岁以上的个体进行卒中相关因素的基线调查 ,包括脑卒中史、高血压病史、糖尿病史及吸烟史等 ,同时检测血浆Fg、空腹血糖、血脂、血压、红细胞压积、血小板等 ,分析Fg与脑卒中及其危险因素之间的关系。结果　武警部队 35岁以上人群平均血浆Fg水平为 (2 .83± 0 .6 7)g/L ,较国内常人水平稍低。缺血性脑卒中患者血浆Fg水平则明显偏高。Fg增高与缺血性卒中 ,年龄、高血压、高胆固醇、红细胞压积及血小板水平密切相关。结论　武警部队 35岁以上人群血浆Fg总体水平较国内常人水平稍低。Objective To investigate the serum fibrinogen (Fg) levels in Armed Police Forces (APF)personnel aged 35 years and over,and the relationships between Fg levels and stroke and associated risk factors.Methods A cohort study was carried out in 2 731 subjects randomly sampled from APF.A baseline survey was conducted,including history of stroke,and hypertension, and stroke-associated diseases,and laboratory profile,such as Fg, glucose, triglycerides, cholesterol,and hematocrit.The relationships between Fg and stroke and associated risk factors were analyzed.Results Serum Fg level in APF personnel was (2.83±0.67) g/L,slightly lower than that in general population in China.Fg was increased in patients with cerebral infarction.Increase in Fg level was also closely associated with hypertension,age,hyper cholesterolemia, hematocrit, platelet, and smoking.Conclution The serum Fg level in APF personnel aged 35 year and over is slightly lower than that in general population in China.Fg level correlates closely with ischemic stroke and associated risk factors.

关 键 词：武警部队 35岁以上人群 血浆 纤维蛋白原 脑血管病 调查 

分 类 号：R743[医药卫生—神经病学与精神病学]