应用滤膜法作抗菌滴眼剂菌数测定的研究  

Study on the detection of bacterial amount in antibiotic eye drops by membrane filtration

作　　者：詹云丽[1] 王小慧[1] 李楚云[2] 

机构地区：[1]广东省惠州市药品检验所,广东惠州516001 [2]惠州市中心人民医院,广东惠州516001

出　　处：《中国现代应用药学》2004年第4期309-311,共3页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的　建立抗菌滴眼剂菌数测定的方法。方法　采用常规法和薄膜过滤法 ,对抗菌滴眼剂中添加活微生物进行回收验证。结果　常规法微生物回收率为 0 ,薄膜过滤法平均回收率大于 6 5 %。OBJECTIVE To establish a method of detecting the bacterial amount in antibiotic eye drops. METHOD Recovery validation of alive microbes added in antibiotic eye drops was fulfilled by routine and by membrane filtration.RESULTS The average microbial recovery was 0 by routine and more than 65% by membrane filtration respectively.CONCLUSION The method of membrane filtration can be used to detect bacterial amount for antibiotic eye drops.

关 键 词：抗菌滴眼剂 细菌总数 薄膜过滤 

分 类 号：R927.31[医药卫生—药学]