傅里叶变换红外光谱仪-微量金刚石池采样附件在药物分析中的应用  

APPLICATION OF INFRARED FOURIER TRANSFORM SPECTROSCOPY-DIAMOND ANVIL CELL (FTIR-DAC) IN DRUG ANALYSIS

作　　者：左跃先[1] 

机构地区：[1]南京市公安局,南京210001

出　　处：《光谱学与光谱分析》1993年第6期35-36,12,共3页Spectroscopy and Spectral Analysis

摘　　要：本文选用常见催眠镇静药及精神失常等类药三十余种,应用傅里叶变换红外光谱仪微量金刚石池附件(FTIR-DAC)采样分析,对于标示药量不低于药重1/3的药物片(粉)剂可以通过直接测试谱图认定药物;对于药物纯品,最低检出量可在2×10^(-7)g;对于薄层层析分离后的药物斑点的检验,以苯巴比妥为例,本法可最低检出5×10^(-6)g。本实验方法检定药物快速、灵敏、准确。A technology for the determination of drug has been developed using FTIR-DAC. More than 30 drugs have been sampled and tested. The minimal detectable quantity were 2×10^(-7)g for the pure drug and 5×10^(-6)g for the drug separated by TLC, e. g. Phenobarbitolum. It is a rapid, sensitive and accurate method to use FTIR-DAC for the drug analysis.

关 键 词：红外光谱仪 采样附件 差谱 药物 

分 类 号：R914.1[医药卫生—药物化学]