24例胃肠间质瘤病理及免疫组化分析  

Pathologic and Immunohistochemical Aanalysis of 24 Cases of Gastrointestinal Stromal Tumor

作　　者：雷德利[1] 王新海[2] 赵晓玲[1] 刘冬玲[1] 

机构地区：[1]武汉市普爱医院病理科,430033 [2]汉川市人民医院病理科

出　　处：《肿瘤防治研究》2004年第9期563-564,F003,共3页Cancer Research on Prevention and Treatment

摘　　要：目的　探讨胃肠间质瘤病理诊断及免疫组化特点。方法　对 2 4例胃肠间质瘤进行常规病理及免疫组化CD117、CD34、SMA、S 10 0染色特点分析。结果　 2 4例胃肠间质瘤由梭形细胞和上皮样细胞组成 ,其中 2 1例CD117和 18例CD34标记阳性 ,阳性表达率分别为 87.5 %和 75 %。结论　胃肠间质瘤是胃肠常见的间叶性肿瘤 ,缺乏定向分化。Objective To investigate the pathologic and immunohistochemical features of CD117 CD34 SMA S-100 and diagnostic criteria of gastrointestinal stromal tumors(GIST). Methods 24 cases of GIST were studied by routine and immunohistochemistry. Results The GISTS showed two bases cell types spindle and epithelioid; 21 cases, tumor cells of GIST were positivery stained for CD117. 18 cases, tumor cells of GIST were positively stained for CD34. Conclusion GIST which have no evidence of specific differentiation constitute the largest category of mesenchymal tumous of gastointestinal tract.The expression of CD117 and CD34 play an improtant role in the diagnosis of GIST.

关 键 词：胃肠间质瘤 免疫组织化学 CD117 CD34 

分 类 号：R735.2[医药卫生—肿瘤] R735.3[医药卫生—临床医学]