166例脊髓髓内肿瘤的临床资料分析  

Clinical analysis of 166 patients with intramedullary spinal cord tumors

作　　者：丁兴华[1] 车晓明[1] 徐启武[1] 

机构地区：[1]复旦大学附属华山医院神经外科,上海200040

出　　处：《中国微侵袭神经外科杂志》2004年第9期388-390,共3页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的探讨脊髓髓内肿瘤的发病规律,提高术前诊断水平。方法总结分析经病理证实的166例脊髓髓内肿瘤病人的临床资料。结果男女比例为1.63 ∶1。肿瘤位于延颈髓16例,颈段57例,颈胸段22例,胸段50例,胸腰段8例,胸腰骶段2例,腰段6例,腰骶段5例。其中室管膜瘤87例,星形细胞瘤41例,血管母细胞瘤16例,海绵状血管瘤8例,脂肪瘤6例,其他少见肿瘤8例。病程平均28.5月,首发症状为自发性疼痛54例(32.5%),感觉异常52例(31.3%),肌力减退45例(27.1%)。结论脊髓髓内肿瘤好发于成年人,男性比女性多见,病程较长;多见于颈段,其次是胸段。首发症状以自发性疼痛最多见。MRI是诊断髓内肿瘤的首选方法,可作出较准确的定位诊断和初步定性诊断,不同类型髓内肿瘤有不同的特征性表现。Objevtive To investigate the diagnosis of intramedullary spinal cord tumors (IMSCT) in children and adults. Methods The database records of 166 patients of IMSCT were reviewed. Results Our study sample comprised 103 men and 63 women, with an average age of 36 years, ranged from 3 to 65 years. 16 cases had medullo-cervical tumors, 57 had cervical tumors, 22 had cervico-thoracic tumors, 50 had thoracic tumors, 8 had thoraco-lumbar tumors, 2 had thoraco-lumbo-sacral tumors, 6 had lumbar tumors, and 5 had lumbo-sacral tumors. 87 cases were ependymomas, 41 were astrocytomas, 16 were hemangioblastomas, 8 were cavernous haemangiomas, 6 were lipomas, and 8 were other uncommon intramedullary tumors. The mean duration of symptoms was 28.5 months. Pain was the most common complaint. Conclusions IMSCT is more frequent in the adults than in the children, and more frequent in men than in women. Patients often have long courses of the disease. The most frequent location is cervical cord, then the thoracic cord. The pain is the most common complaint. MRI is the most important method to the diagnosis of intramedullary spinal cord tumors.

关 键 词：髓内肿瘤 核磁共振成像 诊断 

分 类 号：R739.4[医药卫生—肿瘤]