术前颞浅动脉插管化疗对舌癌切除术预后的影响  

The therapeutic effects of preoperative chemotherapy via cannulation of superficial temporal artery on tbe prognosis of patients with lingual carcinoma excised

作　　者：李创伟[1] 陈恩河[1] 杨冬涛[1] 杨楚[1] 王双乐[1] 林炘[1] 

机构地区：[1]广东省汕头市中心医院耳鼻咽喉-头颈外科,515031

出　　处：《中国中西医结合耳鼻咽喉科杂志》2004年第3期148-149,共2页Chinese Journal of Otorhinolaryngology in Integrative Medicine

摘　　要：目的 探讨术前颞浅动脉插管化疗对舌癌切除术预后的影响。方法 采用随机分组的方法把手术治疗的26例舌癌患者分为两组,术前颞浅动脉插管化疗后行手术治疗组12例,单纯手术治疗组14例。颞浅动脉插管至颈外动脉第二分支(舌动脉)下方,注入顺铂20～30mg/d.5-FU10mg·kg^(-1)·d^(-1),5日为一疗程。结果 术前颞浅动脉插管化疗组术后3年生存率为83.3％,5年生存率为75.0％,高于单纯手术组的3年生存率71.4％,5年生存率57.1％。结论 术前颞浅动脉插管化疗能够提高舌癌患者的术后远期生存率。Objective To investigate the therapeutic effects of preoperative chemotherapy, which was given via the cannulation of superficial temporal artery(STA), on the prognosis of pa- tients with lingual carcinoma excised. Methods Twenty-six cases with lingual carcinoma were randomly divided into two groups, with 12 in treating group (TG) treated by preoperative chemotherapy via STA cannulation and the tumor resection, and 14 in controlling one (CG) treated only by surgery itself. The procedures of preoperative chemotherapy included STA cannu- lation to the level below the opening of lingual artery and drugs infusing(DDP20～30mg/d, 5-FU 10mg/kg/d, 5days as a course). Results The 3-year survival rate of TG was 81. 3% and 5-year survival rate was 75. 0% respectively for patients in TG, significantly higher than those of 75. 0% and 57.1% in CG. Conclusion The procedure of preoperative chemotherapy via STA cannula- tion can improve the long-term survival rate of patients with lingual carcinoma excised.

关 键 词：术前 颞浅动脉插管化疗 舌癌 切除术 预后 

分 类 号：R739.8[医药卫生—肿瘤]