角膜内皮细胞计和超声角膜测厚仪测量角膜中央厚度的比较  

Comparison of central corneal thickness measurements by specular microscopy and ultrasonic pachymetry.

作　　者：张波涌[1] 钟华[1] 袁玲[1] 牛志强[1] 李含玉[1] 袁援生[1] 

机构地区：[1]昆明医学院第一附属医院眼科,云南昆明650032

出　　处：《云南医药》2004年第4期283-285,共3页Medicine and Pharmacy of Yunnan

摘　　要：目的　比较角膜内皮细胞计和超声角膜测厚仪测量的角膜厚度值之间的差异性。方法　分别应用角膜内皮细胞计和超声角膜测厚仪对 5 3例 (10 6眼 )的中央角膜厚度进行测量 ,对两组测量值进行配对t检验、直线相关分析 ,并对两种仪器三次测量值行组内相关系数分析。结果　应用超声角膜测厚仪检测的角膜厚度均值为 (5 2 1 77± 32 16 ) μm ,角膜内皮细胞计数计检测的均值为 (5 15 4 8± 30 39) μm ,后者显著低于前者 (P<0 0 0 1) ,两者呈显著正相关 (r=0 938,P <0 0 0 1) ,超声法和角膜内皮细胞计法测厚的组内相关系数分别为0 95和 0 93。结论　角膜内皮细胞计测量值低于超声测厚仪测量值 ,但从临床角度来看 ,这种差异并不能否定角膜内皮计用于角膜测厚的可靠性 ,角膜内皮细胞计测量值的一致性甚至超过了超声测厚仪 ,并有非接触性检查的优点。角膜内皮细胞计和超声测厚仪均能为我们提供较为准确的角膜厚度值 ,但临床测量时应当知道两种检查方法之间的差异 ,并认识到各自的优劣 ,才能更好地选择应用不同的设备。evaluate the central corneal thickenss values in myope with the new Topcon SP2000P noncontact specular microscopy and ultrasonic pachymetry.Method Central corneal thickenss was measured in 106 eyes of 53 patients first with a noncontact specular microscopy(Topcon SP2000P),then with an ultrasonic pachymetry. Measurements were repeated 3 times for each pachymetry to assess repeatability.Result The mean central corneal thickness was compatible between noncontact specular microscopy(515.48±30.39) and ultrasonic pachymetry(521.77±32.16). The former gave a significantly smaller mean than the latter(P<0.001).There were significant linear correlations between noncontact specular microscopy and ultrasonic pachymetry(r=0.938,P<0.001).The intraclass correlation coefficient(ICC) of the two devices tended to show high repeatability(Separately 0.93 and 0.95).Conclusion Noncontact specular microscopy gives significantly smaller values compared with ultrasonic pachymetry. But central corneal thickness values between noncontact specular microscopy and pachymetry show significant linear correlations and both provide acceptable repeatability of measurements. However, the two devices cannot be simply used interchangeably.

关 键 词：中央角膜厚度 超声角膜测厚仪 角膜内皮细胞计 

分 类 号：R78[医药卫生—口腔医学]