米诺地尔生发液的制备及质量控制  

Studies on Preparation and Quality Standards for Minoxidil Solution

作　　者：吴畏[1] 陈雅[1] 胡大强[1] 舒凌玲[1] 

机构地区：[1]第三军医大学野战外科研究所大坪医院药学部,重庆400042

出　　处：《中国药师》2004年第9期712-713,共2页China Pharmacist

摘　　要：目的 :探讨米诺地尔生发液的制备方法及质量控制。方法 :采用紫外分光光度法测定含量。结果 :米诺地尔在 2～10 μg·ml-1浓度范围内与吸收度呈良好线性关系 (r =0 .9999,n =5 ) ,回收率为 99.84 % ,RSD为 0 .36 % (n =9)。结论 :该制剂稳定、制备简便 。Objective: To develop a preparing method and quality control for minoxidil solution.Method: The content of minoxidil was determined by UV spectrophotometry. Result: Linear relationship was found in the minoxidil concentrations ranging from 2 to 10 μg·ml -1 . The average recovery of minoxidil was 99.84% , RSD = 0.36% ( n =9).Conclusion: Minoxidil solution is stable, simple in preparation technique and accurate in quality control.

关 键 词：米诺地尔 制备 质量控制 

分 类 号：R943[医药卫生—药剂学]