120例乳腺癌骨转移核素显像特点分析  

Analysis of characteristics of radionuclide imaging in 120 patients with breast cancer and skeletal metastasis

作　　者：侯少洋[1] 张月梅[1] 王建军[1] 

机构地区：[1]广东省农垦中心医院,湛江524002

出　　处：《中国肿瘤临床与康复》2004年第4期320-321,共2页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨乳腺癌骨转移患者骨显像的特点及规律。方法120例乳腺癌患者做全身骨核素显像。结果120例乳腺癌患者中有58例骨显像异常,结合临床及X线检查诊断为骨转移,骨转移发生率为48.3%。其中27例年龄≤40岁乳腺癌患者骨转移8例,骨转移发生率为29.6%;93例年龄>40岁乳腺癌患者骨转移50例,骨转移发生率为53.8%,年龄>40岁的乳腺癌患者骨转移发生率明显增加(P<0.05)。58例骨转移患者中49例为多发病灶(占84.5%),9例为单发病灶(占15.5%),每例患者的平均病灶数为4.83个。骨转移的部位以胸部为多见,其余依次为脊柱、骨盆、肢体和颅骨。结论乳腺癌骨转移发生率很高,骨转移的发生有一定的规律及特点,核素全身骨显像对于临床诊断分期及治疗决策有一定的意义。Objective To evaluate the characteristics and regularity of skeletal metastasis in breast cancer.Methods 120 patients with breast cancer were examined by radionuclide bone imaging.Results Of them, 58 were identified as having skeletal metastasis.Coupled with clinical data and X ray examination,the incidence of bone metastasis was about 48.3%.Eight of the 27 patients who aged≤40 were found to have skeletal metastasis,with a skeletal metastasis rate of 29.6%,and 50 out of the other 93 who aged>40 had skeletal metastasis,with a metastasis rate of 53.8%.There was significant difference in incidence of bone metastasis between patients aged >40 and ≤40( P <0.05). Multiple metastatic lesions accounted for 84.5%(49 cases) and solitary 15.5%(9 cases), with an average of 4.83 loci per patient. The site of bone metastasis commonly seen was in the thorax, followed by spine, pelvis, limbs and skull.Conclusion Bone imaging should be performed in the patients with beast cancer, because it is important for evaluate stage and therapy.

关 键 词：乳腺肿瘤 放射性核素显像 骨转移 

分 类 号：R737.9[医药卫生—肿瘤] R730.44[医药卫生—临床医学]