黄连水提取物药膜辅助治疗慢性牙周炎的疗效评价  

The clinical study on the adjunctive effects of aqueous extract from coptis root for the treatment of chronic periodontitis

作　　者：吴益华[1] 姜广水[2] 张世周[3] 边蕙芝[1] 朱少平[1] 

机构地区：[1]济南市口腔医院,山东济南250001 [2]山东大学口腔医院,山东济南250012 [3]山东省立医院口腔颌面外科,山东济南250021

出　　处：《上海口腔医学》2004年第4期252-255,共4页Shanghai Journal of Stomatology

摘　　要：目的:制备并探讨黄连药膜对慢性牙周炎的辅助治疗作用。方法:应用黄连水提取物制备药膜;将30例患有中到重度慢性牙周炎患者的各4颗牙随机分为4组:黄连药膜组、碘甘油组、空白药膜对照组和空白对照组。在基线、4周和7周时分别检测菌斑指数(PI)、探诊深度(PD)、附着丧失(AL)和探诊出血(BOP)等牙周病的临床指标。对资料进行方差分析和卡方检验。结果:各组在4周和7周时,探诊深度、附着丧失和探诊出血与基线比较均有显著性差异(P<0.05);黄连药膜组治疗效果优于其他各组(P<0.05),且治疗结束后,各项指标呈继续改善状态。结论:机械治疗后,应用黄连药膜辅助治疗,可以显著提高牙周炎的治疗效果。PURPOSE: To make a therapeutic membrane with aqueous extract from coptis root and explore its adjunctive effects for treating chronic periodontitis. METHODS: Drug membrane from coptis root aqueous extract was developed; 4 teeth in 30 patients with moderate to advanced periodontitis were randomly divided into four groups: coptis root membrane, iodine glycerin, single drug membrane and blank control group. All parameters including plaque index (PI), probing depth(PD), attachment loss(AL) and bleeding on probing (BOP)were measured at baseline, 4 and 7 weeks after treatment. Analysis of variance and chi-square test were carried out for analysis. RESULTS: In all four groups, there were significant differences of PD, AL, BOP between baseline and 4,7 weeks after treatment(P < 0.05), the treatment effect of coptis root membrane was significantly superior to that of other three groups (P < 0.05). Moreover, all the parameters improved continuously. CONCLUSION: Use of coptis root membrane as an adjunctive method after scaling can significantly improve the treatment effect of periodontitis.

关 键 词：黄连 牙周病 刮治 根面平整 

分 类 号：R781.4[医药卫生—口腔医学]