IgY牙膏对口腔变形链球菌的抑制作用  

The inhibitive effect of IgY toothpaste against oral Streptococcus mutans

作　　者：池政兵[1] 高艳霞[1] 潘瑛[1] 张濒 冯希平 

机构地区：[1]上海第二医科大学附属第九人民医院口腔医学院口腔预防儿童科 [2]上海市口腔医学研究所,上海200011

出　　处：《上海口腔医学》2004年第4期256-258,共3页Shanghai Journal of Stomatology

摘　　要：目的:研究含生物活性物IgY牙膏对口腔变形链球菌的抑制作用。方法:将140位受试者随机分成实验组和对照组。每位受试者经过2个月洗脱期后,分别使用实验牙膏和空白对照牙膏。采用Dentoclt SM方法分别测出基线值和使用1d、3d、7d、1个月后以及停止使用牙膏后2周的口腔变形链球菌水平。结果:①实验组受试者口腔中变形链球菌水平的下降发生在使用实验牙膏刷牙后第1天,而对照组则发生在刷牙后的第3天。②随着刷牙时间延长,2组受试者口腔中变形链球菌水平逐步下降。③实验组停止使用实验牙膏刷牙后2周,仍有抑制变形链球菌的作用。结论:与对照组相比,实验组牙膏有增强抑制口腔变形链球菌的作用。PURPOSE: To study the effect of the toothpaste containing IgY against oral Streptococcus mutans. METHODS: 140 subjects were divided into 2 groups randomly (test group and control group). Before the beginning of the test, every subject underwent a elution period in order to lessen the other interference factors, then used different toothpastes were used respectively and the test began. Streptococcus mutans values were determined with Dentocult SM Strip just before test, at 1,3,7,30days after toothpaste used and 14 days after stopping toothpaste used. RESULTS: ①In test group, Streptococcus mutans values decreased at 1 day after toothpaste used. In control group Streptococcus mutans values decreased at 3 days after toothpaste used.②Streptococcus mutans values decreased gradually in each groups after toothpaste used.③In test group, 2 weeks after stopping toothpaste used,Streptococcus mutans values were still suppressed. CONCLUSION: The application of the toothpaste containing IgY may reduce oral Streptococcus mutans levels significantly.

关 键 词：龋病 唾液 变形链球菌 IGY 牙膏 

分 类 号：R780.1[医药卫生—口腔医学]