综合性医院抑郁症的特点及疗效分析  

Depression in General Hospital and Therapeutic Effect of Paroxetine

作　　者：罗盛[1] 蒋云[1] 吴恺[1] 王新德[1] 

机构地区：[1]北京医院神经内科,100730

出　　处：《中国心理卫生杂志》2004年第8期587-589,共3页Chinese Mental Health Journal

摘　　要：目的 :了解综合性医院神经内科门诊抑郁症的临床特点及抗抑郁治疗的临床疗效。方法 :对46例抑郁症患者的临床特点进行研究分析 ,同时对其中 2 4例患者给予帕罗西汀治疗 ,对汉密尔顿抑郁评定表 (HAMD)的平均总分数、汉密尔顿 4因子及临床总体印象量表 (CGI)评分在治疗前后进行比较。结果 :46例抑郁症患者均以不同程度的躯体症状为主诉 ,临床表现多种多样 ,可涉及全身各系统 ;其中 2 4例抑郁症患者给予帕罗西汀治疗后 ,汉密尔顿抑郁评定表的平均总分数、汉密尔顿 4因子及临床总体印象量表评分分数在治疗后较治疗前显著减少 (P <0 0 1)。结论 :了解抑郁症患者躯体症状的临床特点 ,对于抑郁症的诊断和治疗至关重要。Objective: To study the clinical features of depressive patients consulting neurological clinics in a general hospital and the therapeutic effect of Paroxetine in treatment of depression in this group Methods: 46 patients with depressive symptoms were collected consecutively, 24 among them were treated by Paroxetine The changes of scores of HAMD and Clinical Global Impression(CGI) before and after treatment were used to assess the therapeutic effect Results: Patients complained a variety of somatic symptoms involved nearly all systems, After four weeks’treatment of Paroxetine, both HAMD and CGI scores decreased dramatically The change of HAMD became significant at the end of the first week of treatment Conclusion: Depressive patients consulting general hospital have many somatic complaints Paroxetine has both anxioletic and antidepressant effects in this group of patients

关 键 词：综合性医院 抑郁症 神经内科 汉密尔顿抑郁评定表 

分 类 号：R749.41[医药卫生—神经病学与精神病学]