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作 者:王钜[1] 卢静[1] 陈振文[1] 孟霞[1] 肖迎秋[1] 姜洪杰[1]
机构地区:[1]首都医科大学实验动物科学部,北京100054
出 处:《中国比较医学杂志》2004年第4期221-223,共3页Chinese Journal of Comparative Medicine
基 金:北京市 2 48工程科技重大项目(实验动物保障支撑体系的建设-"长爪沙鼠生物学特性研究" ;H0 2 0 2 2 0 0 5 0 3 90 )
摘 要:目的 对 75只长爪沙鼠的体重和 11种主要脏器重量进行测定 ,探索与建立清洁级长爪沙鼠主要脏器的生物学指标体系。为动物实验提供必要参数。方法 选择 2~ 3月龄长爪沙鼠 ,雌性 38只 ,雄性 37只 ,分别称体重与 11项脏器重量 ,统计学分析。结果 雌雄长爪沙鼠主要脏器系数均无明显差异 (P >0 0 5 ) ,Kendall和谐系数 (W)分析表明 ,动物与个体各主要器官整体发育协调性较好。体重与脏器线性分析表明 ,胸腺、甲状腺、脑、睾丸无线性关系。心、肝、脾、肺、肾、肾上腺、卵巢等具有明显线性关系。结论 2~ 3月龄的长爪沙鼠主要脏器重量在雌雄之间没有明显差异 ,体重与脏器之间是否存在线性关系 ,因器官而异。Objective The weight of 11 kinds of organ and body weight in 75 Mongolian gerbils were mensurated in order to study and build biology indexes system of main organs in Mongolian gerbils and provide the parameters for animal experiments. Methods 38 female and 37 male Mongolian gerbils aged 2-3 months were selected and their body weight and main organ weight were separately weighed, and the data were analyzed in statistics.Results There were no significant differences in main organ weight by sexes( P >0 05),and the growth of main organs of animal community was in a good harmony through the analysis of Kendall coefficient. The linear analysis about body weight and organs showed there were obvious linear relations except thymus,thyroid,brain and testis.Conclusions There are no significant differences in the main organ weight of Mongolian gerbils aged 2-3 months by sexes, and whether there is linear relation between body weight and organs lies on different organs.
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