尿毒症患者的抑郁状态及其相关因素分析  

Depressive state and its related factors in patients with uremia

作　　者：马力群[1] 付荣国[1] 王莉[1] 张星映[1] 

机构地区：[1]西安交通大学第二医院肾病内科,陕西省西安市710004

出　　处：《中国临床康复》2004年第27期5758-5759,共2页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:探讨尿毒症患者抑郁的发生率及其相关影响因素,为心理支持和针对性治疗提供依据。方法:采用Zung抑郁自评量表(SDS)对98例尿毒症患者进行心理状态调查,分别评分并进行比较分析。结果:尿毒症患者有70%(69/98)存在不同程度的抑郁状态;在分析比较中,初期透析患者抑郁发生较多;存在并发症者抑郁发生情况与无并发症者相比,差异有显著性意义(χ2=21.05,P<0.01);抑郁患者发生头昏头痛、睡眠障碍、疲劳及皮肤瘙痒的情况与无抑郁患者相比,差异有显著性意义(χ2=29.60,28.77,22.16,P<0.01);社交隔离和医疗费用高、经济窘迫、家庭支持差等因素在抑郁患者中发生情况显著高于无抑郁患者(χ2=29.60,28.77,22.16,P<0.01);有无抑郁患者的性别、年龄、文化程度之间差异无显著性意义(χ2=0.5835,0.7098,2.17,P>0.05)。结论:尿毒症患者存在着较高的抑郁发生率并受多种因素影响。在治疗躯体疾病的同时应重视预防和缓解患者的抑郁状态,以促进精神生理的康复,延缓尿毒症进展。AIM:To explore the incidence rate of depression and the related influencing factors in patients with uremia,and provide evidence for psychological support and therapy. METHODS:Zung depressive self evaluation scale(SDS) was used to investigate the mental state in 98 uremic patients, and then the scores were analyzed. RESULTS:Depressive state of different extents occurred in 70%(69/98) of the uremic patients.Patients undergoing hemodialysis in the initial stage had higher incidence of depression.The incidence of depression was significantly higher in the patients companied by complication than those without complication(χ2=21.05,P< 0.01).The incidence of headache,dizzy,sleep disorder,tiredness and itch of skin were significantly higher in patients with depression then those without depression(χ2=29.60,28.77,22.16,P< 0.01).The social intercourse insulation, economic misery and bad family support occurred more in patients with depression than those without depression(χ2=29.60,28.77,22.16,P< 0.01). The incidence of depression in uremic patients was not correlated with gender, age and educational level(χ2=0.583 5,0.709 8,2.17,P >0.05). CONCLUSION:The incidence rate of depression in uremic patients is higher. Medical and nursing staff should fully pay attention to the treatment of depression simultaneously,application of proper intervention,so as to prevent and relieve the depression state of the patients,accelerate the psychophysiological rehabilitation,and postpone the progress of uremia.

关 键 词：尿毒症 抑郁障碍 因素分析 统计学 

分 类 号：R749[医药卫生—神经病学与精神病学]