精神分裂症和情感性精神障碍患者探究性眼球轨迹运动的比较  

Comparison of exploratory eye tracking movement between patients with schizophrenia and affective disorder

作　　者：韩永华[1] 王丽莉[2] 朱日升[1] 刘粹[1] 周凤 吕淑艳 王秀丽[5] 小岛卓也[6] 松岛英介 沈渔村[1] 

机构地区：[1]北京大学精神卫生研究所,北京市100083 [2]天津市精神卫生中心,天津市300074 [3]宁夏回族自治区固原精神病院,宁夏回族自治区固原市756000 [4]天津市康宁医院,天津市300000 [5]通辽市精神病院,内蒙古自治区通辽市028000 [6]日本大学神经精神教研室 [7]日本医科齿科大学神经精神科教研室

出　　处：《中国临床康复》2004年第27期5868-5870,共3页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:探讨眼球轨迹运动在精神分裂症患者、情感性精神障碍患者、正常对照人群各种指标的差异,以及在精神医学中的临床应用意义。方法:应用眼球轨迹运动标记纪录仪(MODELⅣ,日本提供)对符合国际疾病分类第10版和中国精神疾病分类方案第二版修订版的诊断标准的498例患精神分裂症患者、110例情感性精神障碍患者及81例正常对照人群进行测试。根据判别分析结果犤DiscriminantAnalysis,D分值=(10.265-0.065×眼球注视点+0.871×反应性探索分)犦分析它们各自对D分值敏感性。判别分析结果获正分为精神分裂症性患者,获负分为非精神分裂症性患者。比较眼球轨迹运动在精神分裂症患者组、情感性精神障碍组以及正常对照人群组的组间差异。结果:498例精神分裂症患者获正分386例,负分112例,精神分裂症对D分值敏感性77.5%。眼球轨迹运动的各项指标在精神分裂症患者阳性症状和阴性症状间比较其差异无显著性意义(t=0.08～1.36,P>0.05);110例情感性精神病组获正分70例,负分40例,情感性精神病对D分值特异性为36.4%;81人正常对照人群获正分7例,负分74例,其D分值的特异性为91.4%。眼球轨迹运动的各项指标在正常对照人群与精神分裂症患者组、情感性精神障碍组的组间比较其差异均有非常显著性(t=3.31～17.00,P<0.01)。结论:精神?AIM:To explore the difference of exploratory eye tracking movement(EETM) among patients with schizophrenia,affective disorder and normal controls,and its clinical significance in psychological medicine. METHODS:A total of 498 patients with schizophrenia and 110 with affective disorders,who were in accordance with the diagnostic criteria of the tenth edition of International Classification of Diseases(ICD) and the second edition of Chinese Classification of Mental Disorders(revised),and 81 normal controls received examinations by using the eye tracking movement labeling recorder(MODEL Ⅳ,provided by Japan).The results of discriminant analysis(D score=10.265-0.065×point of eyeball fixation+0.871×reactive exploratory score) were used to analyze their sensitivity and validity to D scores.Patients with positive score of DA were diagnosed to have schizophrenia,and those with negative scores had no schizophrenia.The differences of EETM among the patients with schizophrenia,affective disorder and the normal controls were compared. RESULTS:Among the 498 patients with schizophrenia,386 cases had positive score and 112 cases had negative score respectively and the sensitivity of schizophrenia to the D score was 77.5%.There were insignificant differences in the indexes of EETM between the positive and negative symptoms in the patients with schizophrenia(t=0.08 to 1.36,P >0.05).Among the 110 patients with affective disorder,70 cases had positive score and 40 cases had negative score,and the specialty of affective disorder to the D score was 36.4%.Seven cases had positive score and 74 cases with negative score in the 81 cases of the normal control group,and its specialty to the D score was 91.4%.The indexes of EETM in the normal control group had very significant differences from those in the schizophrenia group and affective disorder group(t=3.31 to 17.00,P< 0.01). CONCLUSION:The EETM for schizophrenia had higher sensitivity,and were not affected by the different symptoms of schizophrenia.EETM is important in the assist

关 键 词：精神分裂症 情感障碍 精神病性 眼球运动 判别分析 

分 类 号：R749.3[医药卫生—神经病学与精神病学]