肝硬化患者胃液体排空及其与血清NO水平关系的初步研究  

The primary study of the relationship between gastric liquid emptying and serum NO in patient with liver cirrhosis

作　　者：项丹妮[1] 曹忆嵘[1] 林庆民[2] 王根生[1] 曹秀英[1] 赵尚敏[1] 于晓峰[1] 

机构地区：[1]上海华东医院消化内科,200040 [2]上海华东医院超声科,200040

出　　处：《上海医学影像》2004年第3期186-188,共3页Shanghai Medical Imaging

摘　　要：目的 研究肝硬化患者胃液体排空功能及其与血清NO水平关系。 方法 应用实时超声法对33例肝硬化患者(Child-Pugh A级10例,B级17例,C级6例)和14例健康志愿者的胃液体半排空时间进行测定,并测定其空腹血清NO浓度。 结果 肝硬化患者饮牛奶后胃液体半排空时间为48.6±8.71分钟,血清NO浓度为66.46±11.96umol／L;健康对照组则分别为26.14±7.32分钟,50.23±9.7umol／L,均有显著性差异。Child A,B,C三组之间无差别。结论 肝硬化患者胃液体半排空时间延迟,NO在动力延缓中起着重要的作用。实时超声检测法值得推广。Objective To study the relationship between gastric liquid emptying and serum nitric oxide (NO) in patients with liver cirrhosis. Methods Half gastric liquid emptying time (HGLET) of 33 patients with liver cirrhosis (Child A 10 patients, Child B 17, Child C 6 ) and 14 volunteers were tested by means of real time ultrasonography. Their fasting serum NO were also tested. Results HGLET of patients with liver cirrhosis and their serum NO were 48.6±8.71 minutes and 66.46±11.96umol / L, volunteers were 26.14+7.32 minutes and 50.23±9.7umol / L , respectively. There was significant difference between patients and volunteers. There was no statistical difference among patients of Child A, B, and C. Conclusion In liver cirrhosis, HGLET is delayed, NO plays an important role in this process. Real time ultrasonography is a kind of method suggested to be used.

关 键 词：肝硬化 胃液体排空 血清NO 超声检测 

分 类 号：R575.2[医药卫生—消化系统]