对乙酰氨基酚与β—环糊精包合方法的研究  

Study on properties of PAL—β—cyclodextrin complex

作　　者：郝治湘[1] 王坤瑶 刘蕊[3] 刘影[3] 

机构地区：[1]齐齐哈尔大学化学与化工学院,齐齐哈尔161006 [2]黑龙江汽车改装厂,齐齐哈尔161006 [3]齐齐哈尔大学化学化工学院2003级本科毕业生

出　　处：《齐齐哈尔大学学报（自然科学版）》2003年第4期8-9,共2页Journal of Qiqihar University(Natural Science Edition)

摘　　要：本文采用饱和水溶液和固体研磨两种方法制备对乙酰氨基酚与β—环糊精的包合物,将两种方法进行比较发现,两种包合方法均形成包合物,且最佳摩尔比为1:3。但从工艺角度和收率考虑,固体研磨法有很大的优势。Acetaminophen β-cyclodextrin inclusion complexes were prepared through solid grinding method and saturation solution method ,After compared these two methods, we discovered that though these methods they are all produce compounds and the best mol compare is 1:3.But,thefunction of inclusion complex by grinding method is better than it by saturation solution method.

关 键 词：Β-环糊精 包合物 固体研磨法 对乙酰氨基酚 

分 类 号：TQ460.2[化学工程—制药化工]