直肠癌细胞DNA含量流式细胞仪分析  

Analysis of DNA Content from Cells of Rectal Cancer with Flow Cytometry

作　　者：吕大鹏[1] 丁立[1] 赵廷忠[1] 赵家宏[1] 鄢凤昌[1] 刘立人[1] 马军 陈立君 

机构地区：[1]哈尔滨医科大学三院腹外科 [2]哈市一院血研室

出　　处：《哈尔滨医科大学学报》1993年第1期57-59,共3页Journal of Harbin Medical University

摘　　要：我们应用流式细胞仪分析了62例石蜡包埋直肠癌切片的DNA含量。探讨了与病理学及临床预后的关系。结果显示,62例中有二倍体肿瘤34例,占54.8%;非二倍体肿瘤有28例,占45.2%。二倍体肿瘤病人5年生存率为79.4%;非二倍体肿瘤病人5年生存率为23.7%。DNA含量与肿瘤的预后密切相关,为直肠癌的临床预后的判定提供了新的重要指标。DNA contents in the paraffin embedded sections from 62 patients with rectal cancer were analysed with flow cytometry. The results showed that surviral rate of 5 years was 79.4% in 34 cases with diploid tumors and 28.7% in 28 cases with aneuploid tumors. The DNA content is closely relative to the prognosis and it can be an important index of evaluating prognosis of rectal cancer.

关 键 词：流式细胞仪 生存率 DNA 直肠肿瘤 

分 类 号：R735.370.3[医药卫生—肿瘤]