一例异基因造血干细胞移植后合并非结核分支杆菌肺病——附文献复习  

Pulmonary disease caused by nontuberculous mycobacteria after allogeneic hematopoietic stem cell transplantation——a case report and literature review

作　　者：陈波[1] 吴德沛[1] 孙爱宁[1] 仇惠英[1] 傅琤琤[1] 唐晓文[1] 马骁[1] 金正明[1] 苗瞄[1] 何广胜[1] 刘跃均[1] 赵晔[1] 吴小津[1] 朱霞明[1] 

机构地区：[1]苏州大学附属第一医院血液科江苏省临床免疫重点实验室,215006

出　　处：《中华血液学杂志》2004年第8期470-472,共3页Chinese Journal of Hematology

基　　金：江苏省医学重点人才基金资助项目 (RC2 0 0 2 0 3 3 );江苏省卫生厅重点课题资助项目 (H2 0 13 );江苏省社会发展基金资助项目 (BS2 0 0 2 0 12 )

摘　　要：目的　报道 1例异基因造血干细胞移植 (allo HSCT)后发生非结核分支杆菌 (NTM )肺病患者 ,经抗NTM治疗有效。方法　病例分析及文献复习。结果　 1例急性非淋巴细胞白血病患者完全缓解后行异基因造血干细胞移植 (allo HSCT) ,移植后发生NTM感染 ,经克拉霉素、卷曲霉素、左旋氧氟沙星抗NTM治疗有效。结论　allo HSCT后NTM感染比较少见 。Objective To report a case with pulmonary disease caused by nontuberculous mycobacteria(NTM) after allogeneic hematopoietic stem cell transplantation(allo-HSCT),with a literature review. Methods Case report and literature review. Results A patient with acute non-1ymphocytic leukemia was treated by allo-HSCT. Her NTM lung disease developed after HSCT was successfully treated with a 3 antimicrobials combination of clarithromycin,levofloxacin and capreomycin for 10 months.Conclusion NTM infections are infrequent in allo-HSCT recipients and have a good clinical prognosis if correctly treated.

关 键 词：异基因 造血干细胞移植 合并症 非结核分支杆菌 肺病 HSCT 不良反应 

分 类 号：R733.7[医药卫生—肿瘤]