恶性胶质瘤术后早期放射治疗疗效观察  

The Effect of Early Radiotherapy of Postoperative Malignant Glioma

作　　者：张瞳光[1] 蒋昆[1] 申少媚[1] 宋建军[1] 刘显明[1] 

机构地区：[1]青岛市人民医院,266001

出　　处：《青岛医药卫生》2004年第1期13-14,共2页Qingdao Medical Journal

摘　　要：目的　对恶性胶质瘤手术后早期放射治疗的效果观察。方法　 2 0 0 1～ 2 0 0 3年间收治的 2 5例恶性胶质瘤病人行手术切除后 6～ 8天开始进行的局部的放射治疗 ,放射剂量为 4 0～ 6 0Gy。每 3个月复查颅脑MRI或强化CT。 结果　 3个月 ,6个月 ,9个月复查均未发现有复发的影像学改变 ;2 4个月复发 5例 ,占 2 0 % ,3年无病生存率占 80 %。Objective To study the effect of early radiotherapy of postoperative malignant glioma.Methods From 2001 to 2003,25 patients with malignant glioma entered the study.The patients received local-regional radiotherapy with the total dose of 40～60Gy.The treatment was started from 6～8 days after operation.All patients were followed up with cranial CT or MRI every 3 months.Results No recurrence was observed in 3,6 and 9 months.Five patients(20%) were found to have recurring disease at the time of 24 months after operation.3-year disease-free survival(DFS) rate was 80%.Conclusions Early postoperative radiotherapy may improve the survival time of the patients with malignant glioma.

关 键 词：恶性胶质瘤 术后放疗 早期放射治疗 生存期 复发 

分 类 号：R730.264[医药卫生—肿瘤] R730.55[医药卫生—临床医学]