泮托拉唑预防重症脑出血并发应激性溃疡出血  

Effect of Pantoprezole in Preventing Stress Ulcer Hemorrhage After Severe Cerebral Hemorrhage

作　　者：廖云彪 罗锡彬[1] 赖伟文[1] 

机构地区：[1]广东省深圳市坪山人民医院,518118

出　　处：《实用全科医学》2004年第6期530-531,共2页Applied Journal Of General Practice

摘　　要：目的　观察泮托拉唑治疗重症脑出血并发应激性溃疡出血的疗效。方法　随机将 68例患者分为泮托拉唑组 (38例 )和法莫替丁组 (30例 )进行对比观察。结果　 2组应激性溃疡出血的发生率分别为 2 .6 %和 2 3 .3 % ,脑出血病死率为 1 3 .2 %和 36 .7% ,泮托拉唑组显著低于对照组 (P <0 .0 5)。结论　泮托拉唑预防重症脑出血并发应激性溃疡出血疗效确切 ,且无明显不良反应。Objective To observe the efficacy of pantoprazole in preventing stress ulcer hemorrhage after severe cerebral hemorrhage. Methods 68 patients were divided into two groups randomly: pantoprezole group (38 cases) and famotidine group (30 cases). Results The morbidity of stress ulcer hemorrhage was 2.6% in pantoprezole group and 23.3% in famotidin group, the mortality of cerebral hemorrhage was 13.2% in pantoprezole group and 36.7% in famotidine group. Morbidity and morbidity were significantly lower in pantoprezole group than in famotidine group (P<0.05). Conclusions Pantoprezole is effective in preventing stress ulcer hemorrhage after severe cerebral hemorrhage.

关 键 词：泮托拉唑 重症脑出血 应激性溃疡出血 药物治疗 

分 类 号：R743.34[医药卫生—神经病学与精神病学] R971[医药卫生—临床医学]