滑桃树种壳化学成分的鉴定(英文)  

Identification of chemical constituents of the seed crusts from Trewia nudiflora L.

作　　者：赵沛基[1] 珠娜[1] 沈月毛[1] 

机构地区：[1]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南昆明650204

出　　处：《中国药物化学杂志》2004年第5期287-290,M005,共5页Chinese Journal of Medicinal Chemistry

基　　金：ThisworkwaspartiallysupportedbytheMinistryofScienceandTechnologygrant 2 0 0 1- 5 1;theNa tionalScienceFoundationofChina (30 0 70 0 0 7) ;ChineseAcademyofSciences (KSCX2 -SW - 313)andNaturalScienceFoundationofYunnanProvince (99B0 0 17G)

摘　　要：目的研究滑桃树种壳中的化学成分。方法通过理化性质和光谱数据的分析鉴定了 5个化合物的结构。结果与结论从滑桃树 (TrewianudifloraL .)种壳中分离到 5个化合物。分别鉴定为 :2 ,3 二氢 3,6 ,7 三羟基 1 苯丙吡喃 4 酮(1)、α ,2′ ,4 ,4′ tetrahydroxydidrochalaone(2 )、isoliquiritigenin(3)、3,4 二羟基桂皮醛 (4 )和 β 谷甾醇 (5 ) ,其中化合物 1是新化合物。化合物Aim To study the chemical co nstituents of the seed crusts from Trewia nudiflora L.Method Five compounds were confirmed by the physical and chemical properties an d the data of spectra.Result and conclusion The structures of the five compounds were isolated from the seed crusts of T rewia nudiflora and determined to be 2,3-dihydro-3,6,7-trihydroxy-1-H -benzo[b]pyran-4-one(1),α ,2′,4,4′-tetrahydroxydidrochalaone(2),isoliquiritigenin(3),3-(3,4- dihydroxyphenyl)-prop-2-en-1-ol(4),β-sitosterol(5).Among thos e,compound 1 was determined to be a new compound,named nudiflone.Compound 3 showed antibacterial activity.

关 键 词：药物化学 分离 鉴定 色谱分析 滑桃 2 3-二氢.3 6 7-三羟基-1-苯丙吡喃-4-酮 

分 类 号：R284.1[医药卫生—中药学]