^(51)Cr释放试验和细胞集落抑制试验测定LAK活性的比较研究  

A comparative study of ^(51)Cr releasing assay and lymphocyte colony inhibition test for detecting LAK activity

作　　者：张庆华[1] 郭伟[1] 张君平[1] 

机构地区：[1]上海第二医科大学附属第九人民医院,上海200011

出　　处：《核技术》1993年第11期701-704,共4页Nuclear Techniques

摘　　要：用于测定细胞毒研究的^(51)Cr释放试验与传统的细胞集落抑制试验相比呈高度相关性,相关系数r=0.9915(p<0.001);在检测LAK淋巴因子激活的杀伤细胞活性方面有简便和实用等优点。51Cr releasing assay has been widely used for detecting cytotoxicity. The correlation coefficient between 51Cr and traditional cyto-colony inhibition test was 0.9915(p<0.001), thereby this method may be available for cytotoxicity detection. The advantages and disadvantages of the two methods for cytotoxicity were compared and discussed. 51Cr releasing assay was considered to be much simpler and quicker, also can be recommended to be used in clinical practice.

关 键 词：杀伤细胞 淋巴细胞 活度 铬51 

分 类 号：R817.1[医药卫生—影像医学与核医学]