1981～2000年天津市区儿童白血病死亡分析  

Analysis on causes of death of childhood leukemia from 1981 to 2000 in the city of Tianjin

作　　者：陈可欣[1] 武光林[2] 何敏[1] 董淑芬[1] 王继芳[1] 钱碧云[1] 

机构地区：[1]天津市肿瘤医院肿瘤研究所,300060 [2]天津医科大学公共卫生学院

出　　处：《中华儿科杂志》2004年第8期617-620,共4页Chinese Journal of Pediatrics

基　　金：国家重点医学科技攻关项目"九五"基金资助(96-906-01-01)

摘　　要：目的 对天津市1981～2000年儿童白血病死亡率进行统计分析,了解其变化趋势。方法 全部死亡资料取自天津市肿瘤医院登记报告中心。病例按照国际疾病分类(ICD-0)进行编码。根据有关年份人口数,按年龄、性别和病例的死亡时间计算死亡率和死亡发病比。结果 1981-2000年儿童白血病死亡病例共计239例(男性129人,女性110人);儿童白血病年龄别死亡率变化波动较大,其中以0-4岁组死亡率最高;天津市儿童白血病死亡发病比平均为0.51,1981～2000年儿童白血病死亡率呈缓慢下降趋势,急性淋巴细胞性、急性粒细胞性和慢性粒细胞性白血病是三种最常见的儿童白血病类型,分别占儿童肿瘤总数的69.3％、20.9％和8.0％。结论上述死亡趋势变化,提示除了白血病诊断和报告情况的改善外,居民生活方式和某些环境因素的变化在儿童白血病的发生中起着一定的作用。因此在儿童白血病防治、危险因素的研究中,应结合儿童白血病的发病特点,确定研究的重点和防治对策。Objective Leukemia is a major cause of death of children in China, which accounts for 50 % of all cancers of children. Data from Tianjin Cancer Hospital was analyzed for mortality of leukemia in children under 20 years from 1981 to 2000 in the city of Tianjin. Methods All physicians and medical staff of the hospitals and clinics in the registry area were responsible for filling out the report forms for every new case diagnosed as malignant tumors. Death certificates for malignant tumors have been registered at the local police station and the residential files were checked. All cancer cases with insufficient information were traced to his/her family and relevant persons worked in the clinic. Tianjin Cancer Registry Center periodically conducted an active re-checking program to review all patient records on cancers that was not registered in this period. Tumors diagnosed in this study were coded according to the International Classification of Diseases for Oncology (ICD-O). Mortality rates were calculated by age, sex and date of death. Results The types of acute lymphoid leukemia, acute myeloid leukemia and chronic myeloid leukemia were the most common types of childhood leukemia in Tianjin, comprised 69. 3% ,20. 9 % and 8.0% , respectively. The mortality for childhood leukemia decreased slowly during the period of 1981 to 2000 in Tianjin. Mortality and morbidity ratios were 0. 51. Conclusion Combined with characteristics of individual forms of childhood leukemia mortality, further epidemiological research is needed to prevent childhood leukemia

关 键 词：1981~2000年 天津市区 儿童 白血病 死亡 

分 类 号：R733.7[医药卫生—肿瘤]