胆固醇结石中细菌的电镜观察  

Observation of Bacteria in Cholesterol Stones by Electronic Microscope

作　　者：杨玉龙 谭文翔 刘小北 李雪驼[2] 

机构地区：[1]大连市肝胆外科研究所友谊医院肝胆外科,大连116001 [2]中科院大连化学物理研究所,大连116001

出　　处：《中国普外基础与临床杂志》2004年第5期447-449,共3页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的　通过电镜观察胆固醇结石内细菌的存在。方法　选取我院接受手术治疗的 12例胆石症患者 ,男 6例 ,女 6例 ,平均年龄 5 4 .6岁 ( 35～ 72岁 ) ,其中胆囊结石 5例 ,肝内外胆管结石 1例 ,胆总管结石并胆囊结石 6例。利用透射电镜对结石进行细菌学观察。结果　在胆固醇结晶中和结石核心均发现有细菌样结构 ,呈卵圆形及长卵圆形 ,菌壁样结构不清晰 ,内部结构基本消失 ,细胞器、细胞核等结构均不可见。结论　胆固醇结石中有细菌样物质存在 ,位于结石的核心和外周 。Objective To observe the bacteria in cholesterol stones by electronic microscope and to explore the role of bacteria in the stone formation.Methods Twelve patients with cholelithiasis underwent operations (male 6, female 6, average age 54.6 years) with cholecystolithiasis 5, extrahepatic and intrahepatic bile duct stone 1, common bile duct stone combining with gallstone 6. The cholesterol stones were observed by electronic microscope.Results There were bacterial structures in the cholesterol stones and cholesterol crystals.Conclusion There are bacteria in the core and peripheral of cholesterol stones, which suggests that bacteria may play an initial role in the formation of cholesterol stones.

关 键 词：胆固醇结石 电镜观察 发病机理 细菌学 

分 类 号：R575.6[医药卫生—消化系统]