宫颈癌发病因素及年轻化趋势的探讨  

The analysis of cervical cancer etiology and the trend of young age

作　　者：于黎明[1] 哈春芳[1] 熊英[1] 杨尧华[1] 

机构地区：[1]宁夏医学院附属医院,宁夏银川750004

出　　处：《宁夏医学杂志》2004年第10期613-615,共3页Ningxia Medical Journal

摘　　要：目的　探讨宁夏地区不同时期宫颈癌患者发病构成、临床病理特点及其相关因素的变化。方法　对1988- 1992年间 (前 5年组 )及 1998- 2 0 0 2年间 (后 5年组 )收治的共计 2 77例宫颈癌患者进行回顾性分析 ,根据年龄分为≤ 4 0岁、4 1- 4 9岁、5 0 - 5 9岁、≥ 6 0岁四组。结果　两组平均发病年龄无差异 ,均以 5 0 - 5 9岁为高发组 ,4 0岁以下年轻宫颈癌的发生比率明显升高 ,由前 5年组的 12 .5 %升至后 5年组的 2 8.18% ,P <0 .0 1,具有显著的统计学意义。职业分布教师、干部等高级知识分子的构成比明显下降 ,个体、自由职业者发病率逐年升高。结论　宫颈癌的发生、发展近二十年呈现明显上升趋势和年轻化趋势 ,其发病因素前 5年组多与早婚、早育、多产等传统的因素有关 ,而后 5年组HPV感染及性生活紊乱与宫颈癌的发生。Objective To analyze the prevalence, etiology, presentation and character tics of clinic pathology of women diagnosed with cervical cancer in NingXia in different time.Methods The clinic information of 277 patients were retrospectively analyzed and compared between the group of 1988-1992 with the group of 1998-2002,both of which were divided into four groups: ≤40,41-49,50-59,≥60 years old.Results The group of 50-59 years old was the highest than other groups in both period groups. The percentage of cervical cancer under age of 40 had increased from 12.5% in 1988-1992 group to 28.18% in 1998-2002 group.Conclusion The present data shows a much noticeable trend of an increasing incidence and the younger.The reason is relative to earlier marriage, earlier pregnancy and more deliver in 1988-1992 group.but more likely to the HPV infection as well as sexual factors in 1988-1992 group.

关 键 词：宫颈癌 发病因素 年轻化 

分 类 号：R737.33[医药卫生—肿瘤]