^(18)F-FDGPET显像在肺癌纵隔淋巴结转移诊断中的应用  

^(18)F-FDG positron emission tomography for mediastinal staging of lung cancer

作　　者：刘方颖[1] 张雪林[1] 商健彪[1] 王全师[2] 

机构地区：[1]南方医科大学南方医院影像中心,广东广州510515 [2]南方医科大学南方医院2PET中心,广东广州510515

出　　处：《第一军医大学学报》2004年第10期1186-1187,1191,共3页Journal of First Military Medical University

摘　　要：目的探讨^(18)F-FDG PET显像对肺癌肺门及纵隔淋巴结转移的诊断价值。方法41例手术病理证实为肺癌的患者,回顾分析其术前胸部PET对肺门、纵隔淋巴结转移的检出结果,与同期胸部CT检查对比,并以病理为标准。结果经理检出有肺门或纵隔淋巴结转移者18例,PET正确诊断17例,CT正确诊断10例;病理未见肺门或纵隔淋巴结转移者23例,PET正确诊断22例,CT正确诊断20例;^(18)F-FDG PET显像对肺门及纵隔淋巴结转移灶检出的灵敏度和准确性(分别为94.4%、95.1%)明显高于CT(分别为55.6%、73.2%)(P<0.05)。结论^(18)F-FDG PET显像对于肺癌纵隔及肺门淋巴结转移灶的检出具有明显优势,特别是对CT难以检出的小淋巴结转移灶有重要的临床价值,可为临床准确分期、确定治疗方案提供重要依据。Objective To evaluate the diagnostic value of ^(18)F-FDG positron emission tomography (PET) in mediastinal staging of lung cancer. Method A retrospective analysis of mediastial staging was carried out in 41 cases of lung cancer by comparing the preoperative mediastinal FDG PET and CT findings with the pathological results. Results According to the pathological results, 18 patients had mediastinal matestasis, 17 of whom were correctly identified by FDG PET, and 10 by CT. Of the other 23 patients without mediastinal mateatasis pathologically, 22 were correctly diagnosed by FDG PET and 20 by CT. The sensitivity and accuracy for diagnosis of regional mediastinal lymph node matestasis with FDG PET were 94.4% and 95.1%, obviously higher than those of CT (55.6% and 73.2%, P<0.05). Conclusion FDG PET is a better alternative for mediastinal staging of lung cancer, specially for identification of small lymph node metastasis escaping detection by CT, to provide important evidence for clinical staging and treatment planning of lung cancer.

关 键 词：肺肿瘤 淋巴转移 纵隔肿瘤 体层摄影术 发射型计算机 体层摄影术 计算机 ^18F-脱氧葡萄糖 

分 类 号：R734.2[医药卫生—肿瘤] R814.42[医药卫生—临床医学]