春雷霉素高产菌株US95^#的选育及大罐发酵工艺控制  

Screening and fermentation processing control of US95# - a high yielding Chunlei Mycin bacterial strain

作　　者：金昌燮 朴顺爱 崔英兰 金星 郭小威 

机构地区：[1]延边春雷生物药业有限公司,吉林延吉133000

出　　处：《生物学杂志》2004年第5期34-35,44,共3页Journal of Biology

摘　　要：紫外线与光修复交替处理春雷霉素产生菌得到了高产突变株,再结合自然分离选出了US95#。该菌株不但产量高,还具有稳定的遗传性能,并在大罐良好发酵工艺控制和条件下,罐发酵水平在春雷霉素生产上有了重大突破,发酵水平比历史最高水平提高12.9%。Treated by ultraviolet rays and light repair alternatively,a high yield Chunlei Mycin producing mutants were obtained by natural screening method.This bacterial strain not only had higher production but also had a stable hereditary character.By controling the condition and quality process of big fermentor,the tank style fermentation level showed obvious breakthrough in the production and fermentation rate had been raised 12% higher than that of historical record.

关 键 词：春雷霉素 紫外线 光修复 发酵工艺 

分 类 号：TQ455.5[化学工程—农药化工]