子宫肌瘤患者及接受UAE治疗后血清性激素水平分析  

Analysis of the Levels of Serum Steroid Hormones in Patients with Carcinoid in Uterus After Uterine Arterial Embolization

作　　者：廖军[1] 黄锦华[1] 陈凤金[1] 

机构地区：[1]广州市第一人民医院检验科,广州510180

出　　处：《热带医学杂志》2004年第5期598-600,共3页Journal of Tropical Medicine

摘　　要：目的探讨性激素在子宫肌瘤发病中的意义。方法采用化学发光技术检测正常对照者61例(对照组)、子宫肌瘤患者61例(患者组)以及44例子宫肌瘤接受子宫动脉栓塞治疗(UAE)后的患者,血清促卵泡成熟激素(FSH)、促黄体生成激素(LH)、雌激素(E2)、垂体泌乳素(PRL)、睾酮(T)水平。结果子宫肌瘤患者组的血清FSH、LH、PRL、T水平均明显高于对照组;血清E2水平与对照组无显著差异。其中44例接受UAE治疗的子宫肌瘤患者术后血清LH、E2、PRL、T水平均比术前明显降低,FSH与术前无显著差异;术后血清FSH、PRL、T水平均明显高于对照组,LH、E2水平明显低于对照组。结论PRL、T是子宫肌瘤的发病因素。Objective To study the significance of steroid hormone level in the pathogenesis of carcinoid in uterine. Methods The concentration of follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), prolactin (PRL) and testosterone(T) in serum were measured by chemiluminescent enzyme immunoassay in 61 healthy women as controls, 61 patients with myoma of uterus, 44 patients with uterine arterial embolization (UAE). Results The concentrations of FSH, LH, PRL, and T in patients with carcinoid in uterine were significantly higher than that of the controls. There was no difference in E2 compared with the controls. The postoperative concentrations of LH, E2, PRL, and T in serum in 44 patients with UAE were significantly lower than the preoperative concentrations. There is no significant difference in FSH compared with the preoperative concentration. The postoperative concentrations of FSH, PRL and T were significantly higher than that of the controls. The postoperative concentrations of LH and E2 were significantly lower than the controls. Conclusion PRL and T may be the factors of causing uterine leiomyoma.

关 键 词：子宫肌瘤 促卯泡成熟激素 促黄体生成激素 雌激素 垂体泌乳素 睾酮 子宫动脉栓塞治疗 

分 类 号：R737.33[医药卫生—肿瘤]