老年性黄斑变性对生存质量的影响  

Effect of age-related maculopathy on the quality of life

作　　者：邹海东[1] 柏林[1] 刘海芸[1] 张皙[1] 

机构地区：[1]上海交通大学医学院附属第一人民医院眼科,200080

出　　处：《中华眼底病杂志》2004年第5期303-306,共4页Chinese Journal of Ocular Fundus Diseases

基　　金：上海市卫生局青年基金项目 (1 31 0 1 4 Y8)

摘　　要：目的　评价上海市老年性黄斑变性 (AMD)患者与视功能相关生存质量 (vision relatedhealth quality- of- life,VRQL)以及相关的影响因素。　方法　采用中文版低视力者生存质量量表(Chinese- version low vision quality of life questionnaire,CL VQL)测量 AMD患者和非 AMD对照者各10 5例的 VRQL。　结果　 AMD患者组量表的克郎巴赫 α系数为 0 .97。AMD患者各方面生存质量得分均明显低于对照组。渗出型病变越多 ,AMD病程越长 ,量表得分越低。各维和总体量表得分与较佳眼、较差眼视力均相关。较佳眼远视力是影响 AMD患者各方面 VRQL 的首要独立因素。　结论　 AMD主要通过影响视力使患者的 VRQL 受到进行性的损害。采用 CL VQL 可以提供 AMD患者全面的 VRQLObjective To assess the vision-related quality of life(VRQL) in patients with age-related maculopathy (AMD) and the related factors in Shanghai. Methods The VRQL of 105 patiens with AMD and 105 without (the control group) in Shanghai was investigated via Chinese-version low vision quality of life questionnaire. Resutls The Cronbach α coefficient of the questionnaire is 0.97 in the patients with AMD, whose scores of the various quality of life were significantly lower than those in the control group. The more the exudative defect happened, or the longer the disease course developed, the lower the sccores were. All the scores of the scales and the total questionnaire were significantly related to the better or worse monocular visual acuity. The better monocular visual acuity was the first independent risk factor affecting all aspects of VRQL in pateints with AMD. Conclusions Decreased visual acutiy may gradually impair the VRQL in patients with AMD. Chinese-version questionnaire of low vision quality of life can provide the general information of the VRQL in patients with AMD.

关 键 词：患者 生存质量 老年性黄斑变性 量表 影响 进行性 独立因素 

分 类 号：R774.5[医药卫生—眼科] G842[医药卫生—临床医学]