贲门癌术前化疗栓塞的疗效评价  

Evaluation of TACE before resection of cardiac cancer

作　　者：梁志会[1] 崔进国[1] 潘新元[1] 周桂芬[1] 田惠琴[1] 米学伟[1] 

机构地区：[1]白求恩国际和平医院放射科,石家庄050082

出　　处：《介入放射学杂志》2004年第4期334-336,共3页Journal of Interventional Radiology

摘　　要：目的　探讨贲门癌术前化疗栓塞的疗效、不良反应及对手术切除率的影响。方法　贲门癌患者 5 6例 ,分为TACE组和单纯手术组。TACE组 2 5例 ,测量TACE后其大小、形态的变化、肿瘤坏死的程度及不良反应 ,7～ 15d后行手术切除 ,统计手术时间、术中出血量、手术切除率及生存时间 ,并与单纯手术组 31例进行比较。结果　①TACE可使肿瘤发生一定程度的坏死 ,并使病变范围有所缩小 ,不良反应轻微。②TACE后再行手术切除 ,不仅可提高手术切除率 ,还可减少手术时间及术中出血量 ,延长了生存时间。结论　贲门癌术前行TACE ,创伤轻微 ,疗效显著 ,应作为术前的一项常规治疗。Objective To evaluate the effect of transarterial chemoembolization (TACE) before operation, including side effects and the improvment for the suceesfult resection rate.Methods 56 patients with cardiac cancer were divided into two groups: TACE group and resection group. The former included 25 patients (male 14, female 11) undertaken TACE 7-15 days before surgery. The image manifestations, histological changes and side effects together with the time of operation, volume of blood lose during operation and the succesful resection rate were compared with those of the latter. Results 1. TACE induced the necrosis of tumor tissue to some extent and possessed the power to localize the lesion with little side effects. 2. TACE before resection did not only minimize the injury of operation but also improved the resection rate. Conclusion TACE is a safe, effective modality before operation and is worthy for recommendation

关 键 词：TACE 贲门癌 术前化疗 手术切除率 栓塞 不良反应 术中出血量 手术时间 疗效评价 坏死 

分 类 号：R735.2[医药卫生—肿瘤]