文拉法辛与氟西汀治疗抑郁症的疗效比较  

Curative Effect Comparasion of Venlafaxine and Fluoxetine in Treating Depression.

作　　者：马振武[1] 李梅香[1] 孟庆伟[1] 郭本玉[1] 

机构地区：[1]新乡医学院第二附属医院精神科,河南省新乡市453002

出　　处：《中国全科医学》2004年第18期1335-1336,共2页Chinese General Practice

摘　　要：目的　比较文拉法辛和氟西汀治疗抑郁症的疗效及安全性。方法　 85例抑郁症患者随机分为两组 ,文拉法辛组 4 3例予文拉法辛 2 5～ 10 0mg/次 ,口服 ,2次 /d ;氟西汀组 4 2例予氟西汀 2 0mg/次 ,口服 ,1次 /d ,两组均以 6周为 1个疗程。结果　两组患者的疗效及治疗前、后HAMD评分与副作用的评分间差别均无显著性意义 (P >0 0 5 )。结论　文拉法辛治疗抑郁症安全、有效。Objective To compare the clinical efficacy and safety of venlafaxine and fluoxetine in treating depression.Methods 85 patients with depression were randomly divided into 2 groups: venlafaxine group with 43 patients treated with venlafaxine, 25～100mg, po, bid, for 6wk; fluoxetine group with 42 patients treated with fluoxetine, 20mg, po, qd, for 6wk.Results There was no significant difference in curative effect HAMD scores before and after treatment, side function of the two groups. (P>0.05).Conclusion Venlafaxine is a safe and effective drug in treating depression.

关 键 词：治疗前 文拉法辛 抑郁症 氟西汀 疗效比较 口服 HAMD 结论 显著性 目的 

分 类 号：R749[医药卫生—神经病学与精神病学] R735.7[医药卫生—临床医学]