MIC法测定空肠弯曲菌对氯霉素、环丙沙星、萘啶酮酸和红霉素的敏感性的研究  

Determination of susceptibility of complybacter jejuni to chlramphenicol,ciprofloxacin,nalidixic acid and erythromycin by MIC method

作　　者：张濛[1] 张聪恪[1] 张秀丽[1] 廖兴广[1] 高葆真[1] 

机构地区：[1]河南省卫生防疫站,郑州450003

出　　处：《中国卫生检验杂志》2004年第5期540-542,共3页Chinese Journal of Health Laboratory Technology

摘　　要：[目的]研究空肠弯曲菌对氯霉素、环丙沙星、萘啶酮酸和红霉素四种抗生素的敏感性。[方法]采用MIC法,在5%O2、10%CO2、85%N2的微需氧环境中,测定了空肠弯曲菌对氯霉素、环丙沙星、萘啶酮酸和红霉素四种抗生素的敏感性。[结果]14号菌株,17号菌株同时出现了对环丙沙星和萘啶酮酸的耐药性,11号菌株出现了对红霉素的耐药性。[结论]耐药性菌株的出现与农业和畜牧业中大量使用抗生素的使用相符合,应提高警惕。[Objective) To investigate the susceptibility of complybacter jejuni to chlramphenicol,ciprofloxacin,nalidixic acid and erythromycin.[Methods] The susceptibility of complybacter jejuni to chlramphenicol, ciprofloxacin, nalidixic acid and erythromycin was determined by MIC method under the conditions of 5 % O2, 10% CO2 and 85% N2. [ Results] Both strain No. 14 and No. 17 were resistant to ciprofloxacin and nalidixic acid. The strain No. 11 was resistant to erythromyocin.[ Conclusions] The appearance of drug- resistant strains is in consistent with the extensive use of antibiotics in agriculture and livestock farming. We should pay close attention to it.

关 键 词：红霉素 环丙沙星 空肠弯曲菌 氯霉素 抗生素 敏感性 MIC法 耐药性菌株 使用 CO2 

分 类 号：R978[医药卫生—药品] R378[医药卫生—药学]