子宫颈癌患者血清CA125测定及其临床意义  

Significance of Detection of Serum CA125 in Patients with Cervical Carcinome of Uterus

作　　者：韩守威[1] 唐茜萍[1] 彭芝兰[1] 

机构地区：[1]华西医科大学附二院妇产科

出　　处：《华西医学》1993年第1期101-103,共3页West China Medical Journal

摘　　要：采用碘标OC125单克隆抗体药盒,检测23例子宫癌(包括2例复发癌)患者血清CA125浓度。结果显示,21例原发子宫颈癌患者术前血CA125浓度在5～84u/ml范围,术后CA125浓度为6.1～37.8u/ml范围。手术前后CA125均值差别不明显(p>0.05),血CA125含量与子宫颈癌临床期别之间无明显关联(p<0.05)。两例复发宫颈癌患者血CA125值分别为23.6和14.7u/ml。本研究提示,子宫颈癌患者血清CA125含量测定,对其肿瘤诊断、治疗随访和预后判断意义较小。The presence of serum CA125 was assayed in 23 patients with cervical carcinoma of uterus (including 2 recurrent carcinomas) .The results showed that the concentrations of serum CA125 before and after operation ranged from 5—84 u/ml and 6.1 —37.8 u/ml,respectwely in 21 primary cervical squamous cell carcinomas. The mean CA 125 levels before operation no significant difference to that after operation (p>0.05).The content of serum CA125 was not correlated with the clinical stages of cervical carcinoma (P>0.05). The serum CA125 level in one recurrent squmous cell carcinoma and one recurrent adenocarcinoma of cervix uteri were 23.6U/ml and 14.7U/ml,respectively. Our study suggested that detection of serum CA125 in patients with cervical carcinoma of uterus had limited clinical value for diagnosis, follow-up and prognosis.

关 键 词：宫颈癌 血CA-125 

分 类 号：R737.330.4[医药卫生—肿瘤]