冠元颗粒治疗多发性梗塞性痴呆的随机双盲对照研究  

A Random, Double Blind, Controlled Study of Multi Infarct Dementia Treated with Guan Yuan Granule

作　　者：张裕平[1] 周东[1] 王宏[2] 谢向东 

机构地区：[1]华西医大神经内科 [2]四川省第三人民医院内科 [3]成都市脑血管疾病防治康复中心

出　　处：《华西医学》1993年第1期28-30,共3页West China Medical Journal

摘　　要：本文采用随机、双盲安慰剂研究方法对40例多发性梗塞性痴呆(MID)患者分别用冠元颗粒(Guan Yuan Granues)及安慰剂治疗3月。结果表明治疗组(21例)的精神认识能力(CCSE、FAQ)、血浆粘度、脑电图有明显改善。而对照组(19例)上述各项指标无变化。作者认为冠元颗粒可能通过降低血粘度、增加脑供血量,进而改善脑细胞缺血,促进高级神经功能恢复。49 cases of multi-infarct dementia were treated with Guan Yuan Granule and placebo separately for 3 months by means of ramdom sampling and double blind. The results showed that CCSE, EAQ, plasma viscosity and electroenc-ephalogram improved significantly in treated group. These results suggest that the effects of Gnaa Yuan Granule on decreasing plasma viscosity and increasing cerebral blood flow can improve the blood supply to the ischemc brain area, thus promote the recovery of the brain function

关 键 词：冠元颗粒 梗塞性 痴呆 血浆粘度 

分 类 号：R743.305[医药卫生—神经病学与精神病学]