区域性动脉灌注四联给药治疗重症急性胰腺炎的临床研究  

Regional arterial infusion using four kinds of drugs for treatment of severe acute pancreatitis

作　　者：马凤藻[1] 游凯涛[1] 陈杰[1] 

机构地区：[1]首都医科大学附属北京朝阳医院普外科,北京市100020

出　　处：《中华肝胆外科杂志》2004年第8期536-538,共3页Chinese Journal of Hepatobiliary Surgery

摘　　要：目的　探讨区域性 (胰腺及胰周 )动脉灌注 (RAI)给药治疗重症急性胰腺炎 (SAP) ,以提高胰腺及胰周的给药浓度 ,从而缩短疗程、减少治疗费用、降低死亡率。方法　从 1994年 11月至2 0 0 2年 8月共收治 10 0例重症急性胰腺炎病人 ,按Seldinger法 ,经股动脉插管 ,置管并固定于腹腔动脉干内 ,用输液泵加压持续给药。结果　本组 10 0例病人中 ,死亡 3例 ,死亡率为 3% ,平均住院时间2 5d ,平均住院费用 4 2 5万元 /人。结论　区域性动脉灌注 (RAI)四联给药治疗重症急性胰腺炎方法简单、疗效显著、住院时间短、费用低 ,有较好的社会效益和经济效益。Objective To investigate the therapeutic effects of regional arterial infusion using four kinds of drugs on severe acute pancreatitis (SAP). Methods A total of 100 cases of SAP treated by this method in our hospital from November 1999 to August 2002 were enrolled in this study. Seldinger procedure was used and the tube was sent to celiac artery through femoral artery. Then infusion pump with pressure was applied for continuous drug infusion. Results Three patients died (mortality = 3%). The mean hospital stay was 25 d and average cost RMB42500 yuan/per patient. Conclusions Regional arterial infusion using four kinds of drugs is a simple and effective method for treatment of SAP. It also have the advantages of short hospital stay, low cost and fairly good social and economic benefits.

关 键 词：重症急性胰腺炎 区域性动脉灌注 住院时间 病人 死亡率 临床研究 置管 

分 类 号：R576[医药卫生—消化系统]