232例老年人重症肌无力的临床分析  

The clinical study of myasthenia gravis in 232 elderly patients

作　　者：万顺伦[1] 王红艳 丛志强[3] 

机构地区：[1]济南军区青岛第一疗养院老年科,266071 [2]青岛市交通医院内科 [3]青岛大学医学院附属医院神经科

出　　处：《中华老年医学杂志》2004年第9期609-611,共3页Chinese Journal of Geriatrics

摘　　要：目的　分析老年人重症肌无力 (MG)的有关临床特点。　方法　回顾性分析 2 6年间诊治的 2 32例老年MG患者的临床资料。　结果　老年人MG占总MG病例数 (30 10例 )的比例为7 7%。男性多于女性 ,男∶女 =1 3∶1。老年人MG多在 6 0～ 70岁间发病 ,在其常见首发症状中 ,眼症状 184例 (79 3% )、咽喉肌无力 30例 (12 9% )、肢体肌肉无力 17例 (7 3% )。老年人MG中 ,全身型的构成比多于眼型 (6 2 9%对 37 1% ) ,较少并存自身免疫性疾病和发生危象 ,常合并胸腺瘤 (33例 )及内外科其他疾病 (87例 )。　结论　老年人MG具有独特的临床特点 ,了解这些特点将有利于指导临床诊断和治疗。Objective To investigate the clinical features of myasthenia gravis (MG) in elderly people. Methods Elderly patients among all MG patients observed from February 1977 to February 2003 were respectively reviewed. Results Of 3010 MG patients,232(7.7%) were identified with the onset of the disease after or at the age of 60,and males were more than females with the ratio of 1.3∶1. The first and most commonly seen symptom in the elderly people after MG onset were ocular manifestation,occurring in 79.3%. Bulbar symptoms(12.9%) such as dysarthria and swallowing difficulties were the following symptoms. The systemic form (62.9%) were significantly more than ocular form (37.1%). There were less MG patients with autoimmunity diseases such as thyroid diseases associated with MG than that with the other senile diseases,and the myasthenia crisis were even less in the elderly patients with MG. However,it was found that more MG patients with thymoma than with other thymus abnormality. Conclusions The elderly MG patients had its distinctive clinical features. It is beneficial for diagnosing and treating the MG patients in the elderly people by understanding these clinical features.

关 键 词：老年人 重症肌无力 临床分析 治疗 临床特点 常见 危象 结论 指导 比例 

分 类 号：R746.1[医药卫生—神经病学与精神病学] R161.7[医药卫生—临床医学]