海洛因依赖者执行功能的对照研究  

A Controlled Study of Executive Function in Heroin Addicts

作　　者：杨闯[1] 周家秀[1] 

机构地区：[1]四川大学华西医院精神科,610041

出　　处：《中国心理卫生杂志》2004年第10期682-684,共3页Chinese Mental Health Journal

摘　　要：目的 :探讨海洛因依赖患者执行功能的变化情况。方法 :对 3 6例海洛因依赖患者、 3 6例健康志愿者用木块图形测验、StroopTest (C ,CW )、威斯康星卡片分类试验 (WisconsinCardSortTest ,WCST -M )进行检测 ,测验结果进行对照分析。结果 :海洛因依赖组木块图形总分低于正常对照 ;Stroop (C、CW )总时间、错误次数高于正常对照 ,差异有统计学显著性 (P <0 0 1) ;海洛因依赖组WCST -M测验的错误总数、持续错误总数高于正常对照 ,分类个数低于正常对照 ,差异有统计学意义 (P <0 0 1)。患者海洛因成瘾时间与WCST分类个数呈负相关 (n =3 6,r=-0 3 9;P <0 0 5 )。结论 :海洛因依赖患者大脑执行功能有一定程度的损害。Objective: To investigate the effect of heroin on executive function in heroin addicts Methods: Executive function of thi rty-six heroin addicts and thirty-six normal controls was assessed with a batter y of neuropsychological evaluation instruments in Chengdu city of China The to ols include of block design test, Stroop test (C, CW), Wisconsin card sorting te st (WCST-M)Results: There were significance difference between the two groups, heroin addicts had lower score of Block design and more time spent, number of errors in Stroop test (C、CW) Further more, the addicts had more total error, perseverative err o rs and lower number of categories in WCST than control group (P< 001) There was significance correlation between time of heroin addiction and W CST categories(n=36,r= -039,P<005)Conclusion: There is a certain executive dysfunction of heroin addicts in our objects

关 键 词：海洛因依赖者 正常 患者 对照研究 执行功能 健康志愿者 总数 木块 个数 错误 

分 类 号：R595.5[医药卫生—内科学] R749[医药卫生—临床医学]