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作 者:李步华[1]
机构地区:[1]安徽省滁州市第一人民医院精神科,239000
出 处:《山东精神医学》2004年第4期197-199,共3页Shangdong Archives of Psychiatry
摘 要:目的 探讨氟西汀联用氯硝西泮治疗惊恐障碍前后状态—特质焦虑问卷 (STAI)测查结果变化特点。方法 对 2 8例惊恐障碍病人治疗 6个月 ,分别于疗前、疗后 1、3、6月末以SAI评定焦虑症状 ,以TAI评定焦虑特质 ,以CGI中GI评定临床疗效。结果 药物治疗对焦虑症状有明显疗效 ,疗后各时段与疗前、疗后各时段之间差异均有显著性 (P <0 .0 1) ,而焦虑特质的变化与焦虑症状的变化不同 ,疗后各时段与疗前差异有显著性 (P <0 .0 1) ,但疗后各时段之间基本无变化 (P >0 .0 5 )。GI评定疗后 6月末显效率 85 .7% ,有效率10 0 %。结论 药物治疗对焦虑症状近、远期均有效 ,对焦虑特质近期有效 ,远期基本无效 ,近期效果可能与惊恐情绪所致认知偏差有关 。Objective To explore the changes of STAI before and after medication on panic disorder with fluoxetine plus clonazepam.Methods A total of 28 subjects were treated for 6 months.The anxiety symptoms were assessed with SAI and the anxiety traits were assessed with TAI.The effects were evaluated with GI.Results There had significant improvement after trentment,and there were signficant differences between the end of 1st month, 3th month,6th month after treatment for anxiety symptoms (P<0.01).Anxiety trait changes were not the same as anxiety symptoms,there were no significant difference on anxiety trait between the end of 1st month, 3th month,6th month after treatment.At the end of 6th month,the marked improvement rate was 85.7% and the effective rate was 100%.Conclusion There were improved effects after treatment on anxiety symptoms in short and long stage.There were improved effects after treatment on anxiety trait in short stage,but few effects in long stage.The effects in short stage maybe related with cognitive distortion due to panic mood,whereas it should be treated with psychotherapy.
关 键 词:焦虑症状 药物治疗 惊恐障碍 病人 问卷 远期 结果分析 特质焦虑 时段 结论
分 类 号:R749[医药卫生—神经病学与精神病学] R395.6[医药卫生—临床医学]
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