原发性肝癌五种介入治疗方法的疗效比较  

Comparison in several interventional treatments for large hepatic carcinomas

作　　者：吕毛古[1] 卢秀仙[1] 吴建伟[1] 黄伟[1] 

机构地区：[1]解放军八一医院放射科,南京210002

出　　处：《临床肿瘤学杂志》2004年第5期481-483,共3页Chinese Clinical Oncology

摘　　要：目的 :比较几种介入治疗大肝癌方法优劣。方法 :采用Seldinger技术经股动脉穿刺插管到肝动脉并注入化疗药物和栓塞剂的方法 (TACE) ,合并B超引导下门静脉化疗栓塞 (SPVE)或B超引导下肿瘤内无水酒精注入 (PEI)或结合多频治疗 ;对具备手术条件的患者行Ⅱ期外科手术切除的综合治疗。结果 :TACE ,TACE +SPVE ,TACE +PEI,TACE及Ⅱ期手术切除 ,TACE结合射频治疗的肿瘤缩小率≥ 5 0 % ,分别为 30 2 % ,4 4 9% ,4 5 2 % ,5 8 4 % ;其 1和 2年生存率 ,分别为 36 2 % ,5 7 9% ,70 9% ,94 7% ,96 4 %和 2 2 9% ,39 5 % ,4 1 9% ,6 7 9%。 (TACE结合射频治疗的 2年生存率未随访 )。结论 :大肝癌的综合介入治疗优于单纯TACE治疗。Objective:To compare the characteristics of several interventional treatments in primary hepatic carcinomas.Methods:TACE(transcatheter hepatic arterial chemoembolization); TACE+CPVE(transultrasonic portal vein chemoembolization); TACE+PEI(percutaneous ethanol injecton); TACE+Phase Ⅱ operation; TACE+RF(radio frequency therapy).Results:Rate more than 50% in each group is 30.2%,44.9%,45.2%,58.4%, respectively. One-year survival rate is 36.2%,57.9%,70.9% and 94.7%,respectively. Two-year survival rate is 22.9%,39.5%,41.9%,67.9%(2-year survival rate wasn’t followed up in TACE+RE group), respectively. Conclusion:Comprehensive interventional treatments are better than single TACE in primary hepatic carcinomas.

关 键 词：TACE 肿瘤 介入治疗 大肝癌 疗效比较 原发性肝癌 切除 射频治疗 生存率 SELDINGER技术 

分 类 号：R735[医药卫生—肿瘤] R737[医药卫生—临床医学]