软坚护肝片及甘草甜素片对肝癌术后复发的干预性研究  

The preventive effect of RuanJianHuGanPian and GanCaoTianSuPian on postoperative recurrence in hepatocellular carcinoma

作　　者：梁水庭[1] 覃晓[1] 黎乐群[1] 陆云飞[1] 覃忠[1] 林进令[1] 巫山[1] 梁雪婧[1] 周惠森[1] 

机构地区：[1]广西医科大学第一附属医院肝胆外科,广西南宁530021

出　　处：《临床肝胆病杂志》2004年第5期293-294,共2页Journal of Clinical Hepatology

摘　　要：探索有效、安全、价廉的预防肝癌根治术后复发的药物。对符合入选条件的小肝癌根治术后患者按自愿分为治疗组和对照组。治疗组服用软坚护肝片加甘草甜素片 ,对照组服用葫芦素片加肌苷。治疗 12个月以上 ,长期追踪。治疗组 3、5年肝癌术后复发率 11 6 9%及 15 5 % ,比对照组 30 36 %及 39 2 9%显著低 (P <0 0 5 )。治疗组 3、5年肝癌术后生存率 80 0 %、6 8 8% ,明显高于对照组 5 6 0 %、37 7% (P <0 0 5 )。To probe the effective, safe and economical medicine of preventing recurrence or the second carcinoma after radical resection of hepatocellular carcinoma. Divided the qualified patients after radical resection of small hepatic carcinoma into 2 groups according to their wills. One group had RuanJianHuGanPian and GanCaoTianSuPian for more than 12 months, while the control group had HuLuSuPian and inosine. All of them were long-term followed up. The patients `recurrence rates at 3 and 5 years was 11.69% and 15.55%, which were statistically inferior to that in control group with 30.36% and 39.29% respectively (P<0.05). The patients 3,5years survival rate was 80.0%, 68.8% which were statistically superior to that in the control group with 56.0% and 37.2% respectively. Ruan Jian Hu-Gan Pian cooperating with GanCaoTianSuPian has the advantage of preventing recurrence after radical resection of hepatocellular carcinoma and increase the survival rate.

关 键 词：肝癌 对照组 护肝片 治疗组 甘草甜素 术后复发 根治术后 葫芦素 肌苷 药物 

分 类 号：R735.7[医药卫生—肿瘤]