重症溃疡性结肠炎60例中西医结合治疗效果观察  

Clinical study of integrated traditional and western medicine treatment of critical ulcerative colitis

作　　者：陈治水[1] 贾丹兵[1] 孙旗立[1] 李春雷[1] 李春杰[1] 王宇光[1] 王宇恒[1] 邓伟哲[1] 

机构地区：[1]解放军第211医院,哈尔滨150080

出　　处：《解放军医学杂志》2004年第11期1000-1001,共2页Medical Journal of Chinese People's Liberation Army

摘　　要：目的　观察中西医结合方法治疗重症溃疡性结肠炎的临床疗效。方法　选择 6 0例重症溃疡性结肠炎患者 ,急性发作期以水杨酸和皮质激素治疗为主 ,配合内服中药和苦参槐花合剂保留灌肠 ,缓解期以口服健脾灵为主 ,辅以水杨酸制剂维持治疗半年以上 ,观察其临床疗效和远期随访结果。结果　内科保守治疗 5 5例 ,完全缓解 35例 (6 3 6 % ) ,有效 18例 (32 7% ) ,无效及死亡各 1例 (1 8% )。中转手术治疗 5例(8 3% ) ,完全缓解 4例 ,有效 1例。远期随访 4 3例 ,远期完全缓解率 6 7 4 % ,癌变率 2 3% ,死亡率 4 7% ,手术率 6 9%。结论　中西医结合治疗重症溃疡性结肠炎临床疗效优于单纯西医疗法 ,能明显降低死亡率和手术率。Objective To evaluate the clinical effect of integrated traditional and western medicine in the treatment of serious ulcerative colitis. Methods Salicylate and cortical hormone were given to patients in acute phase, supplemented by oral administration of herbal medicine and retention enema of Kushenhuaihua concoction. During the period of remission, the patients were treated mainly with Jianpiling supplemented with salicylate for at least half a year. Results In 55 patients receiving conservative treatment, 35(63.6%) recovered completely, 18(32.7%) showed effective result, only 1 patient died and another showed ineffective result (1.8%). Five patients underwent surgical treatment, among them 4 were completely relieved. Long-term follow-up showed that in 67.4% of patients the symptoms were completely relieved, and in 2.3% of patients malignant degeneration occurred, 4.7% of the patients died, and 6.9% of the patients underwent operative treatment. Conclusion The effects of integrated traditional and western medicine treatment in patients with serious ulcerative colitis is superior to western medicine aloner as evidenced by a decrease in mortality and necessity of operation.

关 键 词：溃疡性结肠炎 危重型 中西医结合疗法 

分 类 号：R574.1[医药卫生—消化系统]