^(18)F-脱氧葡萄糖双探头hPET/CT显像在原发性食管癌中的应用  

Evaluation of ^(18)F-fluorodeoxyglucose hybrid PET/CT in primary esopha geal carcinoma

作　　者：王剑云[1] 宋康声[1] 车文军[2] 彭寿行[1] 张闻瑞[2] 

机构地区：[1]上海交通大学附属上海市第一人民医院胸外科,200080 [2]上海交通大学附属上海市第一人民医院核医学科,200080

出　　处：《上海医学》2004年第10期724-725,F005,共3页Shanghai Medical Journal

摘　　要：目的　探讨18F 脱氧葡萄糖 (FDG)双探头hPET/CT显像在原发性食管癌中的应用价值。方法　30例经组织病理学证实的原发性食管癌患者行18F FDG双探头hPET/CT显像。同时与近期CT结果进行比较。结果　双探头hPET/CT检测原发性食管癌的灵敏度为 93.3% (2 8/ 30例 )。 2 0例手术患者中 ,食管局部淋巴结转移 14例 ,双探头hPET/CT检出 10例 ,其灵敏度、特异性和准确性分别为 71.4 %、10 0 .0 %和 80 .0 % ,CT检出 4例。双探头hPET/CT检出远处转移 10例 ,CT仅检出 5例。结论　18F FDG双探头hPET/CT诊断原发性食管癌较灵敏 ,在检测食管局部淋巴结转移和远处转移方面可能优于CT。Objective To evaluate the role of 18F-fluorodeoxyglucose(FDG) hPET/CT in detect ion of primary esophageal carcinoma. Methods Thirty patients with confirmed pathology of primary esophageal carcinoma u nderwent whole body hPET/CT imaging. Visual and semiquantitative analysis with s t andardized uptake value (SUV) were used to analyze the images. The results of hP ET/CT study were compared with that of CT. Results The sensitivity of hPET/CT in detection of primary esophageal carcinoma was 93 .3% (28/30). Among the 20 patients who underwent surgery, 14 had regional lymp h no de involvement. Ten of them were detected by hPET/CT, and five by CT, the sensit ivity, specificity and accuracy of FDG hPET/CT were 71.4%, 100.0% and 80.0%, respectively. hPET/CT identified distant metastases in 10 patients, and CT did so only in 5.Conclusion 18F-FDG hPET/CT is a sensitive method for detecting primary esoph ageal carcinoma except the small and early stage lesions. It is more sensitive t han CT in detecting peri-esophagus lymph node involvem ent and distant metastasis, useful for tumor staging.

关 键 词：脱氧葡萄糖 CT 原发性食管癌 双探头hPET/CT 诊断 

分 类 号：R735.1[医药卫生—肿瘤]